HAMAP rule MF_01493

General rule information [?]

Accession	MF_01493
Dates	17-JUN-2014 (Created) 17-FEB-2023 (Last updated, Version 8)

Name	DEAD_helicase_CshA

Scope

Bacteria; Chloroflexota

Bacteria; Bacillota

Template

P96614 (CSHA_BACSU)

Triggered by

HAMAP; MF_01493 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

CSHA

Protein name

RecName:		Full=DEAD-box ATP-dependent RNA helicase CshA;
		EC 3.6.4.13;

Gene name

cshA

Comments [?]

Function	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity.
Catalytic activity	RHEA:13065: ATP + H2O = ADP + H(+) + phosphate EC 3.6.4.13
Subunit	Oligomerizes, may be a member of the RNA degradosome.
Subcellular location	Cytoplasm.
Similarity	Belongs to the DEAD box helicase family. CshA subfamily.

Keywords [?]

ATP-binding
Cytoplasm
Helicase
Hydrolase
Nucleotide-binding
RNA-binding
Stress response

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0003724; Molecular function: RNA helicase activity.
GO:0003723; Molecular function: RNA binding.
GO:0006401; Biological process: RNA catabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS00039; DEAD_ATP_HELICASE; 1;
	PS51192; HELICASE_ATP_BIND_1; 1; trigger=PRU00541;
	PS51194; HELICASE_CTER; 1; trigger=PRU00542;
	PS51195; Q_MOTIF; 1; trigger=PRU00552;
Pfam	PF00270; DEAD; 1;
	PF00271; Helicase_C; 1;

Additional information [?]

Size range	485-552 amino acids
Related rules	MF_01494 (CSHB)
Fusion	None

View rule in raw text format (no links)