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Annotation rule MF_01497
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General rule information [?]

Accession MF_01497
Dates 30-APR-2015 (Created)
19-NOV-2019 (Last updated, Version 5)
Name SrkA_kinase
Scope
Bacteria
Templates P0C0K3 (SRKA_ECOLI); Q8ZKU8 (RDOA_SALTY); Q83IV7 (SRKA_SHIFL): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SRKA
Protein name
RecName: Full=Stress response kinase A;
EC 2.7.11.1;
AltName: Full=Serine/threonine-protein kinase SrkA;
Gene name
srkA

Comments [?]

Function A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
Catalytic activity RHEA:17989: ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]
EC 2.7.11.1
RHEA:46608: ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]
EC 2.7.11.1
Cofactor Mg(2+)
Subunit Monomer.
Subcellular location Cytoplasm.
Similarity Belongs to the SrkA/RdoA protein kinase family.

Keywords [?]


Gene Ontology [?]

GO:0004674; Molecular function: protein serine/threonine kinase activity.
GO:0005524; Molecular function: ATP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01636; APH; 1;

Features [?]

From: SRKA_ECOLI (P0C0K3)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     201     201       Proton acceptor     D  
ACT_SITE     217     217             D  
METAL     206     206       Magnesium     N  
METAL     217     217       Magnesium     D  
SITE     36     36       ATP     S  

Additional information [?]

Size range 280-416 amino acids
Related rules None
Fusion None