HAMAP rule MF_01513
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01513 |
| Accession | MF_01513 |
| Dates | 28-FEB-2005 (Created)
03-SEP-2024 (Last updated, Version 15) |
| Name | Phe_aminotrans_2 |
| Scope(s) |
Bacteria Actinomycetota |
| Template(s) | P9WML5; Q8NTT4; [ Recover all ] |
| Triggered by |
HAMAP; MF_01513 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Protein name | RecName: Full=Aromatic amino acid aminotransferase; Short=ArAT; EC=2.6.1.57; |
| Gene name | Name=pat; |
Comments
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| FUNCTION | Aminotransferase that catalyzes the conversion of aromatic amino acids and 2-oxoglutarate into corresponding aromatic oxo acids and L-glutamate. |
| CATALYTIC ACTIVITY | Reaction=an aromatic L-alpha-amino acid + 2-oxoglutarate = an aromatic oxo-acid + L-glutamate; Xref=Rhea:RHEA:17533, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985, ChEBI:CHEBI:73309, ChEBI:CHEBI:84824; EC=2.6.1.57; |
| COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
| SUBUNIT | Homodimer. |
| SIMILARITY | Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. |
Keywords
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Gene Ontology
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| GO:0008793; Molecular function:aromatic-amino-acid transaminase activity |
| GO:0030170; Molecular function:pyridoxal phosphate binding |
Cross-references
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| Pfam | PF00155; Aminotran_1_2; 1; |
| NCBIfam | TIGR01141; HisC; 1; |
| PROSITE | PS00599; AA_TRANSFER_CLASS_2; 1; |
Features
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| From: PATR_MYCTU (P9WML5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 217 | 217 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
Additional information
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| Size range | 341-373 amino acids |
| Related rules |
MF_01023 |
| Fusion | Nter: None Cter: None |