 |
|
| Annotation rule MF_01524 |
General rule information
[?]
| Accession | MF_01524 |
| Dates | 23-NOV-2004 (Created) 19-NOV-2019 (Last updated, Version 15) |
| Name | CaiC |
| Scope | Bacteria; Enterobacterales |
| Template | P31552 (CAIC_ECOLI) |
| Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
| Identifier |
|
| Protein name |
|
||||||||
| Gene name |
|
Comments
[?]
| Function | Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. |
| Catalytic activity | RHEA:28514: (R)-carnitine + ATP + CoA = (R)-carnitinyl-CoA + AMP + diphosphate
EC 6.2.1.48 |
| RHEA:30079: ATP + CoA + crotonobetaine = AMP + crotonobetainyl-CoA + diphosphate | |
| RHEA:55960: 4-(trimethylamino)butanoate + ATP + CoA = AMP + diphosphate + gamma-butyrobetainyl-CoA | |
| Pathway | Amine and polyamine metabolism; carnitine metabolism. |
| Similarity | Belongs to the ATP-dependent AMP-binding enzyme family. |
Keywords
[?]
Gene Ontology
[?]
GO:0016405; Molecular function: CoA-ligase activity.
Cross-references
[?]
Additional information
[?]
| Size range | 510-518 amino acids |
| Related rules | None |
| Fusion | None |