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Annotation rule MF_01551
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General rule information [?]

Accession MF_01551
Dates 28-NOV-2005 (Created)
19-NOV-2019 (Last updated, Version 17)
Name 23SrRNA_methyltr_M
Bacteria; Proteobacteria
Template P0ADR6 (RLMM_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribosomal RNA large subunit methyltransferase M;
AltName: Full=23S rRNA (cytidine2498-2'-O)-methyltransferase;
AltName: Full=23S rRNA 2'-O-ribose methyltransferase RlmM;
Gene name

Comments [?]

Function Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
Catalytic activity RHEA:42788: cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
Subunit Monomer.
Subcellular location Cytoplasm.
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.

Keywords [?]

Gene Ontology [?]

GO:0008757; Molecular function: S-adenosylmethionine-dependent methyltransferase activity.
GO:0006364; Biological process: rRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01728; FtsJ; 1;
PIRSF PIRSF028774; UCP028774; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     306     306       Proton acceptor     K  
REGION     221     224       S-adenosyl-L-methionine binding     [CSA]-P-G-G  
BINDING     188     188       S-adenosyl-L-methionine     S  
BINDING     240     240       S-adenosyl-L-methionine     D  
BINDING     260     260       S-adenosyl-L-methionine     D  
BINDING     277     277       S-adenosyl-L-methionine     D  

Additional information [?]

Size range 339-389 amino acids
Related rules None
Fusion None