HAMAP rule MF_01568
General rule information
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| Accession | MF_01568 |
| Dates | 7-AUG-2006 (Created)
12-OCT-2023 (Last updated, Version 9) |
| Name | Ntdp |
| Scope(s) |
Bacteria Bacilli |
| Template(s) | None (); [ Recover all ] |
| Triggered by |
HAMAP; MF_01568 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NTDP |
| Protein name | RecName: Full=Nucleoside triphosphate/diphosphate phosphatase; EC=3.6.1.15; EC=3.6.1.6; |
Comments
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| FUNCTION | Has nucleoside phosphatase activity towards nucleoside triphosphates and nucleoside diphosphates. |
| CATALYTIC ACTIVITY | Reaction=a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'- diphosphate + H(+) + phosphate; Xref=Rhea:RHEA:23680, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474, ChEBI:CHEBI:57930, ChEBI:CHEBI:61557; EC=3.6.1.15; |
| CATALYTIC ACTIVITY | Reaction=a ribonucleoside 5'-diphosphate + H2O = a ribonucleoside 5'- phosphate + H(+) + phosphate; Xref=Rhea:RHEA:36799, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:43474, ChEBI:CHEBI:57930, ChEBI:CHEBI:58043; EC=3.6.1.6; |
| COFACTOR | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; |
| SIMILARITY | Belongs to the Ntdp family. |
Keywords
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Gene Ontology
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| GO:0017111; Molecular function:ribonucleoside triphosphate phosphatase activity |
| GO:0017110; Molecular function:nucleoside diphosphate phosphatase activity |
| GO:0000287; Molecular function:magnesium ion binding |
Cross-references
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| Pfam | PF04167; DUF402; 1; |
| PIRSF | PIRSF028345; UCP028345; 1; |
Features
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| From: NTDP_STAAN (Q7A4T2) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 26 | 26 | /note="Proton donor" | R | ||||||||
| BINDING | 90 | 90 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="1" |
N | ||||||||
| BINDING | 106 | 106 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="1" |
D | ||||||||
| BINDING | 108 | 108 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="2" |
D | ||||||||
| BINDING | 110 | 110 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="1" |
D | ||||||||
| BINDING | 110 | 110 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="2" |
D | ||||||||
| BINDING | 123 | 123 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="2" |
D | ||||||||
| BINDING | 126 | 126 | /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420" /ligand_label="2" |
E | ||||||||
Additional information
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| Size range | 175-196 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |