HAMAP rule MF_01570
General rule information
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Accession | MF_01570 |
Dates | 21-AUG-2006 (Created) 1-JUN-2023 (Last updated, Version 13) |
Name | Pro_tRNA_synth_type2 |
Scope | Bacteria; Alphaproteobacteria
Bacteria; Epsilonproteobacteria |
Template | Q6N5P6 (SYP_RHOPA) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). |
Catalytic activity | RHEA:14305: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)
EC 6.1.1.15 |
Subunit | Homodimer. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0004827; Molecular function: proline-tRNA ligase activity.
GO:0006433; Biological process: prolyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
GO:0004827; Molecular function: proline-tRNA ligase activity.
GO:0006433; Biological process: prolyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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PROSITE | PS50862; AA_TRNA_LIGASE_II; 1; |
Pfam | PF03129; HGTP_anticodon; 1; |
PF00587; tRNA-synt_2b; 1; | |
PRINTS | PR01046; TRNASYNTHPRO; 1; |
NCBIfam | TIGR00409; ProS_fam_II; 1; |
Additional information
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