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| Annotation rule MF_01570 |
General rule information
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| Accession | MF_01570 |
| Dates | 21-AUG-2006 (Created) 19-NOV-2019 (Last updated, Version 12) |
| Name | Pro_tRNA_synth_type2 |
| Scope | Bacteria; Alphaproteobacteria
Bacteria; Epsilonproteobacteria |
| Template | Q6N5P6 (SYP_RHOPA) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). |
| Catalytic activity | RHEA:14305: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)
EC 6.1.1.15 |
| Subunit | Homodimer. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. |
Keywords
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Gene Ontology
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GO:0005524; Molecular function: ATP binding.
GO:0004827; Molecular function: proline-tRNA ligase activity.
GO:0006433; Biological process: prolyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
GO:0004827; Molecular function: proline-tRNA ligase activity.
GO:0006433; Biological process: prolyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| PROSITE | PS50862; AA_TRNA_LIGASE_II; 1; |
| Pfam | PF03129; HGTP_anticodon; 1; |
| PF00587; tRNA-synt_2b; 1; | |
| PRINTS | PR01046; TRNASYNTHPRO; 1; |
| TIGRFAMs | TIGR00409; ProS_fam_II; 1; |
Additional information
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