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| Annotation rule MF_01573 |
General rule information
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| Accession | MF_01573 |
| Dates | 31-OCT-2006 (Created) 19-NOV-2019 (Last updated, Version 14) |
| Name | Pyl_tRNA_synth |
| Scope | Archaea; Methanosarcinales |
| Templates | Q6WRH6 (PYLS_METBA); Q46E77 (PYLS_METBF): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. |
| Catalytic activity | RHEA:19277: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)
EC 6.1.1.26 |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the class-II aminoacyl-tRNA synthetase family. |
Keywords
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Gene Ontology
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GO:0004812; Molecular function: aminoacyl-tRNA ligase activity.
GO:0005524; Molecular function: ATP binding.
GO:0006418; Biological process: tRNA aminoacylation for protein translation.
GO:0005737; Cellular component: cytoplasm.
GO:0005524; Molecular function: ATP binding.
GO:0006418; Biological process: tRNA aminoacylation for protein translation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| PROSITE | PS50862; AA_TRNA_LIGASE_II; 1; |
| Pfam | PF00587; tRNA-synt_2b; 1; |
| TIGRFAMs | TIGR02367; PylS_Cterm; 1; |
| TIGR03912; PylS_Nterm; 1; |
Additional information
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| Size range | 404-478 amino acids |
| Related rules | None |
| Fusion | None |