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Annotation rule MF_01573
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General rule information [?]

Accession MF_01573
Dates 31-OCT-2006 (Created)
19-NOV-2019 (Last updated, Version 14)
Name Pyl_tRNA_synth
Scope
Archaea; Methanosarcinales
Templates Q6WRH6 (PYLS_METBA); Q46E77 (PYLS_METBF): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PYLS
Protein name
RecName: Full=Pyrrolysine--tRNA ligase;
EC 6.1.1.26;
AltName: Full=Pyrrolysyl-tRNA synthetase;
Short=PylRS;
Gene name
pylS

Comments [?]

Function Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
Catalytic activity RHEA:19277: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)
EC 6.1.1.26
Subcellular location Cytoplasm.
Similarity Belongs to the class-II aminoacyl-tRNA synthetase family.

Keywords [?]


Gene Ontology [?]

GO:0004812; Molecular function: aminoacyl-tRNA ligase activity.
GO:0005524; Molecular function: ATP binding.
GO:0006418; Biological process: tRNA aminoacylation for protein translation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS50862; AA_TRNA_LIGASE_II; 1;
Pfam PF00587; tRNA-synt_2b; 1;
TIGRFAMs TIGR02367; PylS_Cterm; 1;
TIGR03912; PylS_Nterm; 1;

Additional information [?]

Size range 404-478 amino acids
Related rules None
Fusion None