HAMAP rule MF_01574

General rule information [?]

Accession	MF_01574
Dates	2-NOV-2006 (Created) 17-FEB-2023 (Last updated, Version 16)

Name

LacG

Scope

Bacteria; Bacillota

Bacteria; Fusobacteriota

Templates

C7N8L9 (LACG_LEPBD); P11546 (LACG_LACLL); P11175 (LACG_STAAU): [Recover all]

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

LACG

Protein name

RecName:		Full=6-phospho-beta-galactosidase;
		EC 3.2.1.85;
AltName:		Full=Beta-D-phosphogalactoside galactohydrolase;
		Short=PGALase;
AltName:		Full=P-beta-Gal;
		Short=PBG;

Gene name

lacG

Comments [?]

Catalytic activity	RHEA:24568: a 6-phospho-beta-D-galactoside + H2O = an alcohol + D-galactose 6-phosphate EC 3.2.1.85
Pathway	Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1.
Similarity	Belongs to the glycosyl hydrolase 1 family.

Keywords [?]

Gene Ontology [?]

GO:0033920; Molecular function: 6-phospho-beta-galactosidase activity.
GO:0005990; Biological process: lactose catabolic process.

Cross-references [?]

Features [?]

From: LACG_LACLL (P11546)

Key From To Description Tag Condition FTGroup

ACT_SITE 160 160 Proton donor E

ACT_SITE 375 375 Nucleophile E

BINDING 19 19 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 Q

BINDING 116 116 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 H

BINDING 159 159 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 N

BINDING 160 160 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 E

BINDING 297 297 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 [ND]

BINDING 428 428 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 [ST]

BINDING 429 429 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 W

BINDING 435 435 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 K

BINDING 437 437 /ligand="D-galactose 6-phosphate" /ligand_id="ChEBI:CHEBI:91004 Y

Additional information [?]