HAMAP rule MF_01579
General rule information
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| Accession | MF_01579 |
| Dates | 2-APR-2007 (Created)
1-JUN-2023 (Last updated, Version 17) |
| Name | 16SrRNA_methyltr_F |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P76273 (RSMF_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01579 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RSMF |
| Protein name | RecName: Full=Ribosomal RNA small subunit methyltransferase F; EC=2.1.1.178; AltName: Full=16S rRNA m5C1407 methyltransferase; AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RsmF; |
| Gene name | Name=rsmF; |
Comments
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| FUNCTION | Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. |
| CATALYTIC ACTIVITY | Reaction=cytidine(1407) in 16S rRNA + S-adenosyl-L-methionine = 5- methylcytidine(1407) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42756, Rhea:RHEA-COMP:10223, Rhea:RHEA-COMP:10224, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; EC=2.1.1.178; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. |
Keywords
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Gene Ontology
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| GO:0016434; Molecular function:rRNA (cytosine) methyltransferase activity |
| GO:0031167; Biological process:rRNA methylation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| PROSITE | PS01153; NOL1_NOP2_SUN; 1; |
| Pfam | PF01189; Nol1_Nop2_Fmu; 1; |
| NCBIfam | TIGR00446; Nop2p; 1; |
| PROSITE | PS01153; NOL1_NOP2_SUN; 1; |
| PROSITE | PS51686; SAM_MT_RSMB_NOP; 1; |
Features
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| From: RSMF_ECOLI (P76273) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 125 | 131 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[ACSV]-[ACPS]-[AGP]-[PQ]-[AG]-[GINS]-K | ||||||||
| ACT_SITE | 247 | 247 | /note="Nucleophile" | C | ||||||||
| BINDING | 149 | 149 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
E | ||||||||
| BINDING | 176 | 176 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
D | ||||||||
| case not <FT:4> | ||||||||||||
| BINDING | 177 | 177 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
G | ||||||||
| end case | ||||||||||||
| BINDING | 194 | 194 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
D | ||||||||
Additional information
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| Size range | 467-505 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |