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HAMAP rule MF_01582

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General rule information [?]

Accession MF_01582
Dates 4-OCT-2007 (Created)
26-JAN-2023 (Last updated, Version 22)
Name Ser_Thr_transp_SstT
Scope
Bacteria; Bifidobacteriales
Bacteria; Bacillota
Bacteria; Pseudomonadota
Template P0AGE4 (SSTT_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SSTT
Protein name
RecName: Full=Serine/threonine transporter SstT;
AltName: Full=Na(+)/serine-threonine symporter;
Gene name
sstT

Comments [?]

Function Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
Catalytic activity RHEA:29575: L-serine(in) + Na(+)(in) = L-serine(out) + Na(+)(out)
PhysiologicalDirection=right-to-left (RHEA:29577)
RHEA:69999: L-threonine(in) + Na(+)(in) = L-threonine(out) + Na(+)(out)
PhysiologicalDirection=right-to-left (RHEA:70001)
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Multi-pass membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0015171; Molecular function: amino acid transmembrane transporter activity.
GO:0015293; Molecular function: symporter activity.
GO:0006865; Biological process: amino acid transport.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

PROSITE PS00713; NA_DICARBOXYL_SYMP_1; 1;
PS00714; NA_DICARBOXYL_SYMP_2; 1;
Pfam PF00375; SDF; 1;
PRINTS PR00173; EDTRNSPORT; 1;

Computed features [?]

case not <OC:Escherichia> and not <OC:Shigella>
General Transmembrane; -; 8-10; trigger=yes;
end case

Features [?]

case <OC:Escherichia> or <OC:Shigella>
From: SSTT_ECOLI (P0AGE4)
Key     From     To       Description   Tag   Condition   FTGroup
INIT_MET     1     1       Removed     M  
TOPO_DOM     2     15       Cytoplasmic        
TRANSMEM     16     36       Helical        
TOPO_DOM     37     45       Periplasmic        
TRANSMEM     46     66       Helical        
TOPO_DOM     67     83       Cytoplasmic        
TRANSMEM     84     104       Helical        
TOPO_DOM     105     142       Periplasmic        
TRANSMEM     143     163       Helical        
TOPO_DOM     164     179       Cytoplasmic        
TRANSMEM     180     200       Helical        
TOPO_DOM     201     217       Periplasmic        
TRANSMEM     218     238       Helical        
TOPO_DOM     239     299       Cytoplasmic        
TRANSMEM     300     320       Helical        
TOPO_DOM     321     331       Periplasmic        
TRANSMEM     332     352       Helical        
TOPO_DOM     353     Cter       Cytoplasmic        
end case

Additional information [?]

Size range 360-434 amino acids
Related rules None
Fusion None