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Annotation rule MF_01609 |
General rule information
[?]
Accession |
MF_01609 |
Dates |
12-APR-2005 (Created) 19-NOV-2019 (Last updated, Version 24) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Archaea>
Protein name |
RecName:
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Full=Glutamate--cysteine ligase;
|
|
EC 6.3.2.2;
|
AltName:
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Full=Gamma-glutamylcysteine synthetase;
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Short=Gamma-GCS;
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Short=GCS;
|
|
else
Protein name |
RecName:
|
Full=Putative glutamate--cysteine ligase 2;
|
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EC 6.3.2.2;
|
AltName:
|
Full=Gamma-glutamylcysteine synthetase 2;
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Short=Gamma-GCS 2;
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|
Short=GCS 2;
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|
end case
case <OC:Archaea>
Function |
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea. |
else
Function |
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity. |
end case
Catalytic activity |
RHEA:13285: ATP + L-cysteine + L-glutamate = ADP + H(+) + L-gamma-glutamyl-L-cysteine + phosphate
EC 6.3.2.2
|
case <OC:Enterobacterales>
end case
Similarity |
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. |
case <OC:Archaea>
GO:0004357; Molecular function: glutamate-cysteine ligase activity.
else
GO:0016879; Molecular function: ligase activity, forming carbon-nitrogen bonds.
end case
Additional information
[?]
Size range |
320-426 amino acids |
Related rules |
None |
Fusion |
Nter: None; Cter: <Unknown>, <Peptidase M20> |