Home  |  Contact
Annotation rule MF_01614
Send feedback

General rule information [?]

Accession MF_01614
Dates 1-JUN-2005 (Created)
19-NOV-2019 (Last updated, Version 15)
Name NamA
Scope
Bacteria; Bacillales
Bacteria; Clostridiales
Template P54550 (NAMA_BACSU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
NAMA
Protein name
RecName: Full=NADPH dehydrogenase;
EC 1.6.99.1;
Gene name
namA

Comments [?]

Function Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes.
Catalytic activity RHEA:13149: A + H(+) + NADPH = AH2 + NADP(+)
EC 1.6.99.1
Cofactor FMN
Subunit Homotetramer.
Similarity Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003959; Molecular function: NADPH dehydrogenase activity.
GO:0010181; Molecular function: FMN binding.
GO:0050661; Molecular function: NADP binding.

Cross-references [?]

Pfam PF00724; Oxidored_FMN; 1;

Features [?]

From: NAMA_BACSU (P54550)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     23     26       FMN     [SP]-P-M-C  
NP_BIND     307     308       FMN     [AG]-R  
REGION     164     167       Substrate binding     H-x-x-H  
BINDING     28     28       Substrate     Y  
BINDING     60     60       FMN; via amide nitrogen     A  
BINDING     102     102       FMN     Q  
BINDING     215     215       FMN     R  

Additional information [?]

Size range 337-346 amino acids
Related rules None
Fusion None