HAMAP rule MF_01624
General rule information
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| Accession | MF_01624 |
| Dates | 7-DEC-2005 (Created) 1-JUN-2023 (Last updated, Version 20) |
| Name | Arsenate_reduct |
| Scope | Bacteria; Bacillota |
| Templates | P0A006 (ARSC_STAAU); P45947 (ARSC_BACSU): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. |
| Catalytic activity | RHEA:43848: [thioredoxin]-dithiol + arsenate + H(+) = [thioredoxin]-disulfide + arsenite + H2O
EC 1.20.4.4 |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily. |
Keywords
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case <FT:4> or <FT:5>
end case
Gene Ontology
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GO:0030612; Molecular function: arsenate reductase (thioredoxin) activity.
GO:0005737; Cellular component: cytoplasm.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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Features
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| From: ARSC_STAAU (P0A006) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 10 | 10 | Nucleophile | C | ||||||||
| ACT_SITE | 82 | 82 | Nucleophile | C | ||||||||
| ACT_SITE | 89 | 89 | Nucleophile | C | ||||||||
| DISULFID | 10 | 82 | Redox-active; alternate | C-x*-C | ||||||||
| DISULFID | 82 | 89 | Redox-active; alternate | C-x*-C | ||||||||
Additional information
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| Size range | 130-160 amino acids |
| Related rules | None |
| Fusion | None |