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HAMAP rule MF_01624

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General rule information [?]

Accession MF_01624
Dates 7-DEC-2005 (Created)
1-JUN-2023 (Last updated, Version 20)
Name Arsenate_reduct
Scope
Bacteria; Bacillota
Templates P0A006 (ARSC_STAAU); P45947 (ARSC_BACSU): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ARSC
Protein name
RecName: Full=Arsenate reductase;
EC 1.20.4.4;
Gene name
arsC

Comments [?]

Function Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
Catalytic activity RHEA:43848: [thioredoxin]-dithiol + arsenate + H(+) = [thioredoxin]-disulfide + arsenite + H2O
EC 1.20.4.4
Subcellular location Cytoplasm.
Similarity Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.

Keywords [?]

case <FT:4> or <FT:5>
end case

Gene Ontology [?]

GO:0030612; Molecular function: arsenate reductase (thioredoxin) activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF01451; LMWPc; 1;
NCBIfam TIGR02691; arsC_pI258_fam; 1;

Features [?]

From: ARSC_STAAU (P0A006)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     10     10       Nucleophile     C  
ACT_SITE     82     82       Nucleophile     C  
ACT_SITE     89     89       Nucleophile     C  
DISULFID     10     82       Redox-active; alternate     C-x*-C  
DISULFID     82     89       Redox-active; alternate     C-x*-C  

Additional information [?]

Size range 130-160 amino acids
Related rules None
Fusion None