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HAMAP rule MF_01624

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General rule information [?]

Accession MF_01624
Dates 7-DEC-2005 (Created)
1-JUN-2023 (Last updated, Version 20)
Name Arsenate_reduct
Scope(s) Bacteria
Template(s) P0A006 (ARSC_STAAU); P45947 (ARSC_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01624 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ARSC
Protein name RecName: Full=Arsenate reductase;
Gene name Name=arsC;

Comments [?]

FUNCTIONCatalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
CATALYTIC ACTIVITY Reaction=[thioredoxin]-dithiol + arsenate + H(+) = [thioredoxin]- disulfide + arsenite + H2O; Xref=Rhea:RHEA:43848, Rhea:RHEA- COMP:10698, Rhea:RHEA-COMP:10700, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29242, ChEBI:CHEBI:29950, ChEBI:CHEBI:48597, ChEBI:CHEBI:50058; EC=;
SIMILARITYBelongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0030612; Molecular function:arsenate reductase (thioredoxin) activity
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF01451; LMWPc; 1;
NCBIfam TIGR02691; arsC_pI258_fam; 1;

Features [?]

From: ARSC_STAAU (P0A006)
Key From To Description Tag Condition FTGroup
ACT_SITE 10 10 /note="Nucleophile" C
ACT_SITE 82 82 /note="Nucleophile" C
ACT_SITE 89 89 /note="Nucleophile" C
DISULFID 10 82 /note="Redox-active; alternate" C-x*-C
DISULFID 82 89 /note="Redox-active; alternate" C-x*-C

Additional information [?]

Size range 130-160 amino acids
Related rules None
Fusion Nter: None Cter: None

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