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Annotation rule MF_01633
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General rule information [?]

Accession MF_01633
Dates 3-JUL-2006 (Created)
19-NOV-2019 (Last updated, Version 19)
Name QueC
Scope
Bacteria
Archaea
Templates P77756 (QUEC_ECOLI); O31675 (QUEC_BACSU); Q6D820 (QUEC_PECAS): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
QUEC
case <OC:Bacteria>
Protein name
RecName: Full=7-cyano-7-deazaguanine synthase;
EC 6.3.4.20;
AltName: Full=7-cyano-7-carbaguanine synthase;
AltName: Full=PreQ(0) synthase;
AltName: Full=Queuosine biosynthesis protein QueC;
else case <OC:Archaea>
Protein name
RecName: Full=7-cyano-7-deazaguanine synthase;
EC 6.3.4.20;
AltName: Full=7-cyano-7-carbaguanine synthase;
AltName: Full=Archaeosine biosynthesis protein QueC;
AltName: Full=PreQ(0) synthase;
end case
Gene name
queC

Comments [?]

Function Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
Catalytic activity RHEA:27982: 7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate
EC 6.3.4.20
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Pathway Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
case <OC:Firmicutes>
Subunit Homodimer.
end case
Similarity Belongs to the QueC family.

Keywords [?]

case <FTGroup:1>
end case
case <OC:Bacteria>
end case

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0016879; Molecular function: ligase activity, forming carbon-nitrogen bonds.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
case <OC:Bacteria>
GO:0008616; Biological process: queuosine biosynthetic process.
end case

Cross-references [?]

Pfam PF06508; ExsB; 1;
TIGRFAMs TIGR00364; TIGR00364; 1;
PIRSF PIRSF006293; ExsB; 1;

Features [?]

From: QUEC_BACSU (O31675)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     10     20       ATP        
METAL     186     186       Zinc     C   1
METAL     195     195       Zinc     C   1
METAL     198     198       Zinc     C   1
METAL     201     201       Zinc     C   1

Additional information [?]

Size range 196-269 amino acids
Related rules None
Fusion Nter: <type-2 glutamine amidotransferase domain>; Cter: None