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Annotation rule MF_01660 |
General rule information
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Accession |
MF_01660 |
Dates |
23-MAY-2008 (Created) 19-NOV-2019 (Last updated, Version 13) |
Propagated annotation
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Identifier, protein and gene names
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case <OC:Enterobacterales>
Protein name |
RecName:
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Full=2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase;
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Short=SHCHC synthase;
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EC 4.2.99.20;
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else
Protein name |
RecName:
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Full=Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase;
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Short=SHCHC synthase;
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EC 4.2.99.20;
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end case
Function |
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). |
Catalytic activity |
RHEA:25597: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate + pyruvate
EC 4.2.99.20
|
Pathway |
Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 3/7. |
case not <OC:Cyanobacteria>
Pathway |
Quinol/quinone metabolism; menaquinone biosynthesis. |
else case <OC:Cyanobacteria>
Pathway |
Cofactor biosynthesis; phylloquinone biosynthesis. |
end case
Subunit |
Monomer. |
Similarity |
Belongs to the AB hydrolase superfamily. MenH family. |
case not <OC:Cyanobacteria>
end case
GO:0070205; Molecular function: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity.
case not <OC:Cyanobacteria>
GO:0009234; Biological process: menaquinone biosynthetic process.
else case <OC:Cyanobacteria>
GO:0042372; Biological process: phylloquinone biosynthetic process.
end case
Additional information
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Size range |
239-311 amino acids |
Related rules |
None |
Fusion |
None |