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Annotation rule MF_01664
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General rule information [?]

Accession MF_01664
Dates 8-JUL-2008 (Created)
19-MAR-2020 (Last updated, Version 11)
Name HemeA_synth_type1
Scope
Bacteria; Firmicutes
Template P12946 (CTAA_BACSU)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CTAA
Protein name
RecName: Full=Heme A synthase;
Short=HAS;
EC 1.3.-.-;
AltName: Full=Cytochrome aa3-controlling protein;
Gene name
ctaA

Comments [?]

Function Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group.
Pathway Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.
Subunit Interacts with CtaB.
Subcellular location Cell membrane; Multi-pass membrane protein.
Similarity Belongs to the COX15/CtaA family. Type 1 subfamily.

Keywords [?]

Cell membrane
Heme biosynthesis
Membrane
Oxidoreductase
Transmembrane
Transmembrane helix

Gene Ontology [?]

GO:0006784; Biological process: heme A biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF02628; COX15-CtaA; 1;

Computed features [?]

General Transmembrane; -; 8; trigger=yes;

Features [?]

From: CTAA_BACSU (P12946)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING     278     278       Substrate     H  

Additional information [?]

Size range 297-317 amino acids
Related rules MF_01665 (CTAA)
Fusion None
Comments COX15/CtaA type 2 subfamily in MF_01665.


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