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HAMAP rule MF_01668

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General rule information [?]

Accession MF_01668
Dates 29-SEP-2008 (Created)
13-JAN-2023 (Last updated, Version 9)
Name IolC
Scope(s) Bacteria
Bacillota
Vibrionales
Mycoplasma
Template(s) P42414 (IOLC_BACSU); [ Recover all ]
Triggered by HAMAP; MF_01668 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier IOLC
Protein name RecName: Full=5-dehydro-2-deoxygluconokinase;
                 EC=2.7.1.92;
AltName: Full=2-deoxy-5-keto-D-gluconate kinase;
                 Short=DKG kinase;
Gene name Name=iolC;

Comments [?]

FUNCTIONCatalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2- deoxy-D-gluconate (DKGP).
CATALYTIC ACTIVITY Reaction=5-dehydro-2-deoxy-D-gluconate + ATP = 6-phospho-5-dehydro-2- deoxy-D-gluconate + ADP + H(+); Xref=Rhea:RHEA:13497, ChEBI:CHEBI:15378, ChEBI:CHEBI:16669, ChEBI:CHEBI:30616, ChEBI:CHEBI:57949, ChEBI:CHEBI:456216; EC=2.7.1.92;
PATHWAYPolyol metabolism; myo-inositol degradation into acetyl-CoA; acetyl-CoA from myo-inositol: step 5/7.
SIMILARITYBelongs to the carbohydrate kinase PfkB family.

Keywords [?]


Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0047590; Molecular function:5-dehydro-2-deoxygluconokinase activity
GO:0019310; Biological process:inositol catabolic process

Cross-references [?]

PROSITE PS00583; PFKB_KINASES_1; 1;
PROSITE PS00584; PFKB_KINASES_2; 1;
Pfam PF00294; PfkB; 1;

Features [?]


Additional information [?]

Size range 325-339 amino acids
Related rules None
Fusion Nter: None Cter: None



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