HAMAP rule MF_01674

General rule information [?]

Accession	MF_01674
Dates	7-OCT-2008 (Created) 1-JUN-2023 (Last updated, Version 13)

Name	Sep_tRNA_synth

Scope

Archaea

Templates

Q59054 (SEPS_METJA); O30126 (SEPS_ARCFU): [Recover all]

Triggered by

HAMAP; MF_01674 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

SEPS

Protein name

RecName:		Full=O-phosphoserine--tRNA(Cys) ligase;
		Short=O-phosphoserine--tRNA ligase;
		EC 6.1.1.27;
AltName:		Full=Non-canonical O-phosphoseryl-tRNA(Cys) synthetase;
AltName:		Full=O-phosphoseryl-tRNA(Cys) synthetase;
		Short=SepRS;

Gene name

sepS

Comments [?]

Function	Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
Catalytic activity	RHEA:25678: ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O-phospho-L-seryl-tRNA(Cys) EC 6.1.1.27
Subunit	Homotetramer. Interacts with SepCysS.
Similarity	Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.

Keywords [?]

Aminoacyl-tRNA synthetase
ATP-binding
Ligase
Nucleotide-binding
Protein biosynthesis

Gene Ontology [?]

GO:0004812; Molecular function: aminoacyl-tRNA ligase activity.
GO:0005524; Molecular function: ATP binding.
GO:0043039; Biological process: tRNA aminoacylation.

Cross-references [?]

PROSITE	PS50862; AA_TRNA_LIGASE_II; 1;
Pfam	PF01409; tRNA-synt_2d; 2;
NCBIfam	TIGR00470; SepS; 1;

Features [?]

From: SEPS_ARCFU (O30126)

Key From To Description Tag Condition FTGroup

BINDING 186 188 /ligand="substrate H-M-T

BINDING 231 233 /ligand="substrate S-A-S

BINDING 273 274 /ligand="substrate Y-Y

BINDING 325 325 /ligand="substrate N

Additional information [?]

Size range	526-562 amino acids
Related rules	None
Fusion	None

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