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Annotation rule MF_01674
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General rule information [?]

Accession MF_01674
Dates 7-OCT-2008 (Created)
19-NOV-2019 (Last updated, Version 10)
Name Sep_tRNA_synth
Scope
Archaea
Templates Q59054 (SEPS_METJA); O30126 (SEPS_ARCFU): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
SEPS
Protein name
RecName: Full=O-phosphoserine--tRNA(Cys) ligase;
Short=O-phosphoserine--tRNA ligase;
EC 6.1.1.27;
AltName: Full=Non-canonical O-phosphoseryl-tRNA(Cys) synthetase;
AltName: Full=O-phosphoseryl-tRNA(Cys) synthetase;
Short=SepRS;
Gene name
sepS

Comments [?]

Function Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
Catalytic activity RHEA:25678: ATP + O-phospho-L-serine + tRNA(Cys) = AMP + diphosphate + O-phospho-L-seryl-tRNA(Cys)
EC 6.1.1.27
Subunit Homotetramer. Interacts with SepCysS.
Similarity Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.

Keywords [?]

Aminoacyl-tRNA synthetase
ATP-binding
Ligase
Nucleotide-binding
Protein biosynthesis

Gene Ontology [?]

GO:0004812; Molecular function: aminoacyl-tRNA ligase activity.
GO:0005524; Molecular function: ATP binding.
GO:0043039; Biological process: tRNA aminoacylation.

Cross-references [?]

PROSITE PS50862; AA_TRNA_LIGASE_II; 1;
Pfam PF01409; tRNA-synt_2d; 2;
TIGRFAMs TIGR00470; SepS; 1;

Features [?]

From: SEPS_ARCFU (O30126)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     186     188       Substrate binding     H-M-T  
REGION     231     233       Substrate binding     S-A-S  
REGION     273     274       Substrate binding     Y-Y  
BINDING     325     325       Substrate     N  

Additional information [?]

Size range 526-562 amino acids
Related rules None
Fusion None


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