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Annotation rule MF_01676
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General rule information [?]

Accession MF_01676
Dates 9-OCT-2008 (Created)
1-APR-2020 (Last updated, Version 15)
Name AhpD
Scope
Bacteria
Template P9WQB5 (AHPD_MYCTU)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AHPD
Protein name
RecName: Full=Alkyl hydroperoxide reductase AhpD;
EC 1.11.1.28;
AltName: Full=Alkylhydroperoxidase AhpD;
Gene name
ahpD

Comments [?]

Function Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
Catalytic activity RHEA:62636: (R)-N(6)-dihydrolipoyl-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O
EC 1.11.1.28
case <OC:Actinobacteria>
Subunit Homotrimer.
end case
Similarity Belongs to the AhpD family.

Keywords [?]

case <FT:3> or <FT:4>
end case

Gene Ontology [?]

GO:0008785; Molecular function: alkyl hydroperoxide reductase activity.
GO:0016209; Molecular function: antioxidant activity.

Cross-references [?]

Pfam PF02627; CMD; 1;
TIGRFAMs TIGR00777; AhpD; 1;
TIGR00778; AhpD_dom; 1;

Features [?]

From: AHPD_MYCTU (P9WQB5)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     130     130       Proton donor     C  
ACT_SITE     133     133       Cysteine sulfenic acid (-SOH) intermediate     C  
DISULFID     130     133             C-x*-C  
DISULFID     133     133       Interchain (with AhpC); in linked form     C  

Additional information [?]

Size range 173-194 amino acids
Related rules None
Fusion None