HAMAP rule MF_01683

General rule information [?]

Accession	MF_01683
Dates	19-NOV-2008 (Created) 1-JUN-2023 (Last updated, Version 17)

Name	Salvage_MtnK

Scope

Bacteria

Templates

O31663 (MTNK_BACSU); Q9F0P1 (MTNK_KLEPN): [Recover all]

Triggered by

HAMAP; MF_01683 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

MTNK

Protein name

RecName:		Full=Methylthioribose kinase;
		Short=MTR kinase;
		EC 2.7.1.100;

Gene name

mtnK

Comments [?]

Function	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
Catalytic activity	RHEA:22312: 5-(methylsulfanyl)-D-ribose + ATP = ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate EC 2.7.1.100
Pathway	Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 2/2.
Subunit	Homodimer.
Similarity	Belongs to the methylthioribose kinase family.

Keywords [?]

Amino-acid biosynthesis
ATP-binding
Kinase
Methionine biosynthesis
Nucleotide-binding
Transferase

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0046522; Molecular function: S-methyl-5-thioribose kinase activity.
GO:0019284; Biological process: L-methionine salvage from S-adenosylmethionine.

Cross-references [?]

Pfam	PF01636; APH; 1;
PIRSF	PIRSF031134; MTRK; 1;
NCBIfam	TIGR01767; MTRK; 1;

Features [?]

From: MTNK_BACSU (O31663)

Key From To Description Tag Condition FTGroup

BINDING 115 117 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 E-D-L

BINDING 250 252 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 D-[AP]-E

BINDING 44 44 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 N

BINDING 61 61 /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616 K

BINDING 233 233 /ligand="substrate D

BINDING 340 340 /ligand="substrate R

Additional information [?]

Size range	389-407 amino acids
Related rules	None
Fusion	None

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