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HAMAP rule MF_01683

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General rule information [?]

Accession MF_01683
Dates 19-NOV-2008 (Created)
1-JUN-2023 (Last updated, Version 17)
Name Salvage_MtnK
Scope(s) Bacteria
Template(s) O31663 (MTNK_BACSU); Q9F0P1 (MTNK_KLEPN); [ Recover all ]
Triggered by HAMAP; MF_01683 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MTNK
Protein name RecName: Full=Methylthioribose kinase;
                 Short=MTR kinase;
Gene name Name=mtnK;

Comments [?]

FUNCTIONCatalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.
CATALYTIC ACTIVITY Reaction=5-(methylsulfanyl)-D-ribose + ATP = ADP + H(+) + S-methyl-5- thio-alpha-D-ribose 1-phosphate; Xref=Rhea:RHEA:22312, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58533, ChEBI:CHEBI:78440, ChEBI:CHEBI:456216; EC=;
PATHWAYAmino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'- thioadenosine (hydrolase route): step 2/2.
SIMILARITYBelongs to the methylthioribose kinase family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function:ATP binding
GO:0046522; Molecular function:S-methyl-5-thioribose kinase activity
GO:0019284; Biological process:L-methionine salvage from S-adenosylmethionine

Cross-references [?]

Pfam PF01636; APH; 1;
NCBIfam TIGR01767; MTRK; 1;

Features [?]

From: MTNK_BACSU (O31663)
Key From To Description Tag Condition FTGroup
BINDING 115 117 /ligand="ATP"
BINDING 250 252 /ligand="ATP"
BINDING 44 44 /ligand="ATP"
BINDING 61 61 /ligand="ATP"
BINDING 233 233 /ligand="substrate" D
BINDING 340 340 /ligand="substrate" R

Additional information [?]

Size range 389-407 amino acids
Related rules None
Fusion Nter: None Cter: None

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