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Annotation rule MF_01686
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General rule information [?]

Accession MF_01686
Dates 30-JAN-2009 (Created)
19-NOV-2019 (Last updated, Version 6)
Name Thymidy_synth_arch
Scope
Archaea
Template P80305 (TYSY_METTM)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TYSY
Protein name
RecName: Full=Putative thymidylate synthase;
Short=TS;
Short=TSase;
EC 2.1.1.-;
Gene name
thyA

Comments [?]

Function May catalyze the biosynthesis of dTMP using an unknown cosubstrate.
Pathway Pyrimidine metabolism; dTTP biosynthesis.
Subunit Monomer.
Subcellular location Cytoplasm.
Similarity Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.

Keywords [?]

Cytoplasm
Methyltransferase
Nucleotide biosynthesis
Transferase

Gene Ontology [?]

GO:0004799; Molecular function: thymidylate synthase activity.
GO:0006231; Biological process: dTMP biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS00091; THYMIDYLATE_SYNTHASE; 1;
Pfam PF00303; Thymidylat_synt; 1;
PRINTS PR00108; THYMDSNTHASE; 1;
TIGRFAMs TIGR03283; Thy_syn_methano; 1;

Features [?]

From: TYSY_METTM (P80305)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     146     146             C  

Additional information [?]

Size range 209-223 amino acids
Related rules MF_00008 (TYSY)
Fusion None
Comments Bacterial ThyA belong to a separate family (MF_00008).


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