HAMAP rule MF_01696
General rule information
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Accession | MF_01696 |
Dates | 20-SEP-2010 (Created)
1-JUN-2023 (Last updated, Version 15) |
Name | MshB |
Scope(s) |
Bacteria Actinomycetota |
Template(s) | A0R2I7 (MSHB_MYCS2); P9WJN3 (MSHB_MYCTU); [ Recover all ] |
Triggered by |
HAMAP; MF_01696 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | MSHB |
Protein name | RecName: Full=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase; Short=GlcNAc-Ins deacetylase; EC=3.5.1.103; AltName: Full=N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase; |
Gene name | Name=mshB; |
Comments
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FUNCTION | Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. |
CATALYTIC ACTIVITY | Reaction=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate; Xref=Rhea:RHEA:26180, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089, ChEBI:CHEBI:52442, ChEBI:CHEBI:58886; EC=3.5.1.103; |
COFACTOR | Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.; |
SIMILARITY | Belongs to the MshB deacetylase family. |
Keywords
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Gene Ontology
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GO:0008270; Molecular function:zinc ion binding |
GO:0019213; Molecular function:deacetylase activity |
GO:0010125; Biological process:mycothiol biosynthetic process |
Cross-references
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Features
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From: MSHB_MYCTU (P9WJN3) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 13 | 13 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H | ||||||||
BINDING | 16 | 16 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
D | ||||||||
BINDING | 147 | 147 | /ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105" |
H |
Additional information
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Size range | 230-426 amino acids |
Related rules |
MF_01482 |
Fusion | Nter: None Cter: None |