HAMAP rule MF_01696

General rule information [?]

Accession	MF_01696
Dates	20-SEP-2010 (Created) 1-JUN-2023 (Last updated, Version 15)
Name	MshB
Scope(s)	Bacteria Actinomycetota
Template(s)	A0R2I7 (MSHB_MYCS2); P9WJN3 (MSHB_MYCTU); [ Recover all ]
Triggered by	HAMAP; MF_01696 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MSHB
Protein name	RecName: Full=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase; Short=GlcNAc-Ins deacetylase; EC=3.5.1.103; AltName: Full=N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase;
Gene name	Name=mshB;

Comments [?]

FUNCTION	Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
CATALYTIC ACTIVITY	Reaction=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate; Xref=Rhea:RHEA:26180, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089, ChEBI:CHEBI:52442, ChEBI:CHEBI:58886; EC=3.5.1.103;
COFACTOR	Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
SIMILARITY	Belongs to the MshB deacetylase family.

Keywords [?]

Gene Ontology [?]

GO:0008270; Molecular function:zinc ion binding

GO:0019213; Molecular function:deacetylase activity

GO:0010125; Biological process:mycothiol biosynthetic process

Cross-references [?]

Pfam	PF02585; PIG-L; 1;
NCBIfam	TIGR03445; Mycothiol_MshB; 1;

Features [?]

From: MSHB_MYCTU (P9WJN3)

Key

From

Description

Tag

Condition

FTGroup

BINDING

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

BINDING

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

BINDING

147

/ligand="Zn(2+)"
/ligand_id="ChEBI:CHEBI:29105"

Additional information [?]