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HAMAP rule MF_01696

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General rule information [?]

Accession MF_01696
Dates 20-SEP-2010 (Created)
1-JUN-2023 (Last updated, Version 15)
Name MshB
Scope(s) Bacteria
Template(s) A0R2I7 (MSHB_MYCS2); P9WJN3 (MSHB_MYCTU); [ Recover all ]
Triggered by HAMAP; MF_01696 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MSHB
Protein name RecName: Full=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase;
                 Short=GlcNAc-Ins deacetylase;
AltName: Full=N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase;
Gene name Name=mshB;

Comments [?]

FUNCTIONCatalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
CATALYTIC ACTIVITY Reaction=1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate; Xref=Rhea:RHEA:26180, ChEBI:CHEBI:15377, ChEBI:CHEBI:30089, ChEBI:CHEBI:52442, ChEBI:CHEBI:58886; EC=;
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
SIMILARITYBelongs to the MshB deacetylase family.

Keywords [?]

Gene Ontology [?]

GO:0008270; Molecular function:zinc ion binding
GO:0019213; Molecular function:deacetylase activity
GO:0010125; Biological process:mycothiol biosynthetic process

Cross-references [?]

Pfam PF02585; PIG-L; 1;
NCBIfam TIGR03445; Mycothiol_MshB; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 13 13 /ligand="Zn(2+)"
BINDING 16 16 /ligand="Zn(2+)"
BINDING 147 147 /ligand="Zn(2+)"

Additional information [?]

Size range 230-426 amino acids
Related rules MF_01482
Fusion Nter: None Cter: None

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