HAMAP logo

HAMAP rule MF_01701

Send feedback

General rule information [?]

Accession MF_01701
Dates 11-OCT-2004 (Created)
2-SEP-2024 (Last updated, Version 26)
Name ABC_ATPase_CysA
Scope(s) Bacteria
Plastid
Template(s) P16676 (CYSA_ECOLI); [ Recover all ]
Triggered by PROSITE; PS51237 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CYSA
Protein name RecName: Full=Sulfate/thiosulfate import ATP-binding protein CysA;
                 EC=7.3.2.3;
AltName: Full=Sulfate-transporting ATPase;
Gene name Name=cysA;

Comments [?]

case <OC:Bacteria>
FUNCTIONPart of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=sulfate(out) + ATP + H2O = sulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:10192, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3;
CATALYTIC ACTIVITY Reaction=thiosulfate(out) + ATP + H2O = thiosulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:29871, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33542, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3;
SUBUNITThe complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).
end case
case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>)
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <OC:Bacteria> and <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
case <OG:Chloroplast>
FUNCTIONPart of the ABC transporter complex involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=sulfate(out) + ATP + H2O = sulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:10192, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3;
CATALYTIC ACTIVITY Reaction=thiosulfate(out) + ATP + H2O = thiosulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:29871, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33542, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3;
SUBCELLULAR LOCATIONPlastid, chloroplast.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.

Keywords [?]

ATP-binding
case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
case <OC:Bacteria>
Cell membrane
Membrane
end case
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>
Nucleotide-binding
Sulfate transport
Transport
case <OG:Chloroplast>
Chloroplast
Plastid
end case

Gene Ontology [?]

GO:0008272; Biological process:sulfate transport
GO:0015419; Molecular function:ABC-type sulfate transporter activity
case <OCellular component:Bacteria>
GO:0005886; Cellular component:plasma membrane
end case
case <OG:Chloroplast>
GO:0009507; Cellular component:chloroplast
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
Pfam PF03459; TOBE; 1;
NCBIfam TIGR00968; 3a0106s01; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]

# Fix case/else syntax

Additional information [?]

Size range 236-406 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



View rule in raw text format (no links)