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HAMAP rule MF_01701

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General rule information [?]

Accession MF_01701
Dates 11-OCT-2004 (Created)
1-JUN-2023 (Last updated, Version 25)
Name ABC_ATPase_CysA
Scope
Bacteria
Plastid
Template P16676 (CYSA_ECOLI)
Triggered by PROSITE; PS51237

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CYSA
Protein name
RecName: Full=Sulfate/thiosulfate import ATP-binding protein CysA;
EC 7.3.2.3;
AltName: Full=Sulfate-transporting ATPase;
Gene name
cysA

Comments [?]

case <OC:Bacteria>
Function Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:10192: ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in)
EC 7.3.2.3
RHEA:29871: ATP + H2O + thiosulfate(out) = ADP + H(+) + phosphate + thiosulfate(in)
EC 7.3.2.3
Subunit The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).
end case
case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>)
Subcellular location Cell membrane; Peripheral membrane protein.
else case <OC:Bacteria> and <Property:Membrane=2>
Subcellular location Cell inner membrane; Peripheral membrane protein.
end case
case <OG:Chloroplast>
Function Part of the ABC transporter complex involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:10192: ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in)
EC 7.3.2.3
RHEA:29871: ATP + H2O + thiosulfate(out) = ADP + H(+) + phosphate + thiosulfate(in)
EC 7.3.2.3
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.

Keywords [?]

case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2>
end case
case <OC:Bacteria>
end case
case <OG:Chloroplast>
end case

Gene Ontology [?]

GO:0008272; Biological process: sulfate transport.
GO:0015419; Molecular function: ABC-type sulfate transporter activity.
case <OC:Bacteria>
GO:0005886; Cellular component: plasma membrane.
end case
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PF03459; TOBE; 1;
NCBIfam TIGR00968; 3a0106s01; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

Additional information [?]

Size range 236-406 amino acids
Related rules PRU01700
Fusion None