HAMAP rule MF_01701
General rule information
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| Accession | MF_01701 |
| Dates | 11-OCT-2004 (Created)
2-SEP-2024 (Last updated, Version 26) |
| Name | ABC_ATPase_CysA |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P16676 (CYSA_ECOLI); [ Recover all ] |
| Triggered by |
PROSITE; PS51237 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | CYSA |
| Protein name | RecName: Full=Sulfate/thiosulfate import ATP-binding protein CysA; EC=7.3.2.3; AltName: Full=Sulfate-transporting ATPase; |
| Gene name | Name=cysA; |
Comments
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| case <OC:Bacteria> | |
| FUNCTION | Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. |
| CATALYTIC ACTIVITY | Reaction=sulfate(out) + ATP + H2O = sulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:10192, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3; |
| CATALYTIC ACTIVITY | Reaction=thiosulfate(out) + ATP + H2O = thiosulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:29871, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33542, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3; |
| SUBUNIT | The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP). |
| end case | |
| case <OC:Bacteria> and (not defined <Property:Membrane> or <Property:Membrane=1>) | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| else case <OC:Bacteria> and <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| end case | |
| case <OG:Chloroplast> | |
| FUNCTION | Part of the ABC transporter complex involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. |
| CATALYTIC ACTIVITY | Reaction=sulfate(out) + ATP + H2O = sulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:10192, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16189, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3; |
| CATALYTIC ACTIVITY | Reaction=thiosulfate(out) + ATP + H2O = thiosulfate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:29871, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33542, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.3; |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family. |
Keywords
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| ATP-binding | |
| case <OC:Bacteria> and defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| case <OC:Bacteria> | |
| Cell membrane | |
| Membrane | |
| end case | |
| <a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> | |
| Nucleotide-binding | |
| Sulfate transport | |
| Transport | |
| case <OG:Chloroplast> | |
| Chloroplast | |
| Plastid | |
| end case | |
Gene Ontology
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| GO:0008272; Biological process:sulfate transport | |
| GO:0015419; Molecular function:ABC-type sulfate transporter activity | |
| case <OCellular component:Bacteria> | |
| GO:0005886; Cellular component:plasma membrane | |
| end case | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| Pfam | PF03459; TOBE; 1; |
| NCBIfam | TIGR00968; 3a0106s01; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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| # Fix case/else syntax |
Additional information
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| Size range | 236-406 amino acids |
| Related rules |
PRU01700 |
| Fusion | Nter: None Cter: None |