HAMAP rule MF_01712
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_01712 |
| Accession | MF_01712 |
| Dates | 28-FEB-2007 (Created)
02-SEP-2024 (Last updated, Version 26) |
| Name | ABC_ATPase_NikE |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P33594; [ Recover all ] |
| Triggered by |
PROSITE; PS51248 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | NIKE |
| Protein name | RecName: Full=Nickel import ATP-binding protein NikE; EC=7.2.2.11; |
| Gene name | Name=nikE; |
Comments
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| FUNCTION | Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. |
| CATALYTIC ACTIVITY | Reaction=Ni(2+)(out) + ATP + H2O = Ni(2+)(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786, ChEBI:CHEBI:456216; EC=7.2.2.11; |
| SUBUNIT | The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA). |
| case not defined <Property:Membrane> or <Property:Membrane=1> | |
| SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
| else case <Property:Membrane=2> | |
| SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
| end case | |
| SIMILARITY | Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. |
Keywords
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| ATP-binding | |
| case defined <Property:Membrane> and <Property:Membrane=2> | |
| Cell inner membrane | |
| end case | |
| Cell membrane | |
| Membrane | |
| Nucleotide-binding | |
| Ion transport | |
| Transport | |
| Nickel | |
| Nickel transport | |
| Translocase | |
Gene Ontology
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| GO:0015675; Biological process:nickel cation transport |
| GO:0015413; Molecular function:ABC-type nickel transporter activity |
| GO:0005886; Cellular component:plasma membrane |
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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Additional information
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| Size range | 265-275 amino acids |
| Related rules |
PRU01700 |
| Fusion | Nter: None Cter: None |