HAMAP rule MF_01712

General rule information [?]

Accession	MF_01712
Dates	27-JAN-2005 (Created) 26-JAN-2023 (Last updated, Version 24)
Name	ABC_ATPase_NikE
Scope(s)	Bacteria Pseudomonadota
Template(s)	P33594 (NIKE_ECOLI); [ Recover all ]
Triggered by	PROSITE; PS51248 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	NIKE
Protein name	RecName: Full=Nickel import ATP-binding protein NikE; EC=7.2.2.11;
Gene name	Name=nikE;

Comments [?]

FUNCTION	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY	Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate; Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786, ChEBI:CHEBI:456216; EC=7.2.2.11;
SUBUNIT	The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Peripheral membrane protein.
end case
SIMILARITY	Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Ion transport
Transport
Nickel
Nickel transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>

Gene Ontology [?]

GO:0015675; Biological process:nickel cation transport

GO:0015413; Molecular function:ABC-type nickel transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]