HAMAP rule MF_01712
General rule information
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Accession | MF_01712 |
Dates | 27-JAN-2005 (Created)
26-JAN-2023 (Last updated, Version 24) |
Name | ABC_ATPase_NikE |
Scope(s) |
Bacteria Pseudomonadota |
Template(s) | P33594 (NIKE_ECOLI); [ Recover all ] |
Triggered by |
PROSITE; PS51248 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NIKE |
Protein name | RecName: Full=Nickel import ATP-binding protein NikE; EC=7.2.2.11; |
Gene name | Name=nikE; |
Comments
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FUNCTION | Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. |
CATALYTIC ACTIVITY | Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate; Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786, ChEBI:CHEBI:456216; EC=7.2.2.11; |
SUBUNIT | The complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA). |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
end case | |
SIMILARITY | Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. |
Keywords
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ATP-binding | |
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Membrane | |
Nucleotide-binding | |
Ion transport | |
Transport | |
Nickel | |
Nickel transport | |
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> |
Gene Ontology
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GO:0015675; Biological process:nickel cation transport |
GO:0015413; Molecular function:ABC-type nickel transporter activity |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF00005; ABC_tran; 1; |
PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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Additional information
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Size range | 265-275 amino acids |
Related rules |
PRU01700 |
Fusion | Nter: None Cter: None |