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HAMAP rule MF_01712

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General rule information [?]

Accession MF_01712
Dates 27-JAN-2005 (Created)
26-JAN-2023 (Last updated, Version 24)
Name ABC_ATPase_NikE
Scope(s) Bacteria
Pseudomonadota
Template(s) P33594 (NIKE_ECOLI); [ Recover all ]
Triggered by PROSITE; PS51248 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NIKE
Protein name RecName: Full=Nickel import ATP-binding protein NikE;
                 EC=7.2.2.11;
Gene name Name=nikE;

Comments [?]

FUNCTIONPart of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate; Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786, ChEBI:CHEBI:456216; EC=7.2.2.11;
SUBUNITThe complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Ion transport
Transport
Nickel
Nickel transport
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a>

Gene Ontology [?]

GO:0015675; Biological process:nickel cation transport
GO:0015413; Molecular function:ABC-type nickel transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]


Additional information [?]

Size range 265-275 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



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