HAMAP logo

HAMAP rule MF_01712

Send feedback

General rule information [?]

PURL https://purl.expasy.org/hamap/rule/MF_01712
Accession MF_01712
Dates 28-FEB-2007 (Created)
02-SEP-2024 (Last updated, Version 26)
Name ABC_ATPase_NikE
Scope(s) Bacteria
Pseudomonadota
Template(s) P33594; [ Recover all ]
Triggered by PROSITE; PS51248 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NIKE
Protein name RecName: Full=Nickel import ATP-binding protein NikE;
                 EC=7.2.2.11;
Gene name Name=nikE;

Comments [?]

FUNCTIONPart of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY Reaction=Ni(2+)(out) + ATP + H2O = Ni(2+)(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786, ChEBI:CHEBI:456216; EC=7.2.2.11;
SUBUNITThe complex is composed of two ATP-binding proteins (NikD and NikE), two transmembrane proteins (NikB and NikC) and a solute-binding protein (NikA).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATIONCell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATIONCell inner membrane; Peripheral membrane protein.
end case
SIMILARITYBelongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.

Keywords [?]


Gene Ontology [?]

GO:0015675; Biological process:nickel cation transport
GO:0015413; Molecular function:ABC-type nickel transporter activity
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PROSITE PS50893; ABC_TRANSPORTER_2; 1;

Features [?]


Additional information [?]

Size range 265-275 amino acids
Related rules PRU01700
Fusion Nter: None Cter: None



View rule in raw text format (no links)