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Annotation rule MF_01713
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General rule information [?]

Accession MF_01713
Dates 28-JAN-2005 (Created)
19-NOV-2019 (Last updated, Version 18)
Name ABC_ATPase_PhnC
Scope
Bacteria
Archaea
Template P16677 (PHNC_ECOLI)
Triggered by PROSITE; PS51249

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PHNC
Protein name
RecName: Full=Phosphonates import ATP-binding protein PhnC;
EC 7.3.2.2;
Gene name
phnC

Comments [?]

Function Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:18065: ATP + H2O + phosphonate(out) = ADP + H(+) + phosphate + phosphonate(in)
EC 7.3.2.2
Subunit The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Peripheral membrane protein.
end case
Similarity Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Transport
Translocase
Phosphonate transport

Gene Ontology [?]

GO:0015716; Biological process: organic phosphonate transport.
GO:0015416; Molecular function: ATPase-coupled organic phosphonate transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
TIGRFAMs TIGR02315; ABC_phnC; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

Additional information [?]

Size range 240-280 amino acids
Related rules PRU01700
Fusion None
Comments In PSEST two additionnal operons might be present, with a narrow specificity than phophonate transport the first one ptxABC for phosphite transport and htxBCDE for hypophophite transport. Both ABC ATPase are match by the phnC profile due two a high sequence similarity.


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