HAMAP rule MF_01713

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01713
Accession	MF_01713
Dates	26-MAR-2007 (Created) 02-SEP-2024 (Last updated, Version 25)
Name	ABC_ATPase_PhnC
Scope(s)	Bacteria Archaea
Template(s)	P16677; [ Recover all ]
Triggered by	PROSITE; PS51249 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PHNC
Protein name	RecName: Full=Phosphonates import ATP-binding protein PhnC; EC=7.3.2.2;
Gene name	Name=phnC;

Comments [?]

FUNCTION	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.
CATALYTIC ACTIVITY	Reaction=phosphonate(out) + ATP + H2O = phosphonate(in) + ADP + phosphate + H(+); Xref=Rhea:RHEA:18065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16215, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.2;
SUBUNIT	The complex is composed of two ATP-binding proteins (PhnC), two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).
case not defined <Property:Membrane> or <Property:Membrane=1>
SUBCELLULAR LOCATION	Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
SUBCELLULAR LOCATION	Cell inner membrane; Peripheral membrane protein.
end case
SIMILARITY	Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.

Keywords [?]

ATP-binding
case defined <Property:Membrane> and <Property:Membrane=2>
Cell inner membrane
end case
Cell membrane
Membrane
Nucleotide-binding
Transport
Translocase
Phosphonate transport

Gene Ontology [?]

GO:0015716; Biological process:organic phosphonate transport

GO:0015416; Molecular function:ABC-type phosphonate transporter activity

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]

Size range	240-280 amino acids
Related rules	PRU01700
Fusion	Nter: None Cter: None
Comments	In STUST two additionnal operons might be present, with a narrow specificity than phophonate transport the first one ptxABC for phosphite transport and htxBCDE for hypophophite transport. Both ABC ATPase are match by the phnC profile due two a high sequence similarity.