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Annotation rule MF_01717
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General rule information [?]

Accession MF_01717
Dates 11-OCT-2006 (Created)
19-NOV-2019 (Last updated, Version 17)
Name ABC_ATPase_MglA
Scope
Bacteria
Template P0AAG8 (MGLA_ECOLI)
Triggered by PROSITE; PS51260

Propagated annotation [?]


Identifier, protein and gene names [?]

case not <AnyFeature:PS51254>
Identifier
MGLA
Protein name
RecName: Full=Galactose/methyl galactoside import ATP-binding protein MglA;
EC 7.5.2.11;
Gene name
mglA
else
Identifier
RGMG
Protein name
RecName: Full=Putative ribose/galactose/methyl galactoside import ATP-binding protein;
EC 7.5.2.7;
EC 7.5.2.11;
end case

Comments [?]

case <OC:Bacteria> and not <AnyFeature:PS51254>
Function Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:60156: ATP + D-galactose(out) + H2O = ADP + D-galactose(in) + H(+) + phosphate
EC 7.5.2.11
Subunit The complex is composed of two ATP-binding proteins (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).
Similarity Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
else
Function Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system.
Catalytic activity RHEA:29903: ATP + D-ribose(out) + H2O = ADP + D-ribose(in) + H(+) + phosphate
EC 7.5.2.7
RHEA:60156: ATP + D-galactose(out) + H2O = ADP + D-galactose(in) + H(+) + phosphate
EC 7.5.2.11
Similarity Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
end case
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location Cell membrane; Peripheral membrane protein.
else case <Property:Membrane=2>
Subcellular location Cell inner membrane; Peripheral membrane protein.
end case

Keywords [?]

case defined <Property:Membrane> and <Property:Membrane=2>
end case

Gene Ontology [?]

GO:0008643; Biological process: carbohydrate transport.
case not <AnyFeature:PS51254>
GO:0005354; Molecular function: galactose transmembrane transporter activity.
end case
case <OC:Bacteria>
GO:0005886; Cellular component: plasma membrane.
end case

Cross-references [?]

Pfam PF00005; ABC_tran; 1;
PROSITE PS00211; ABC_TRANSPORTER_1; 1;
PS50893; ABC_TRANSPORTER_2; 2; trigger=PRU00434;
case <OC:Bacteria> and <AnyFeature:PS51254>
PS51254; RBSA; 1;
end case

Additional information [?]

Size range 450-550 amino acids
Related rules PRU01700
Fusion None
Comments Some of these proteins are related to two differents sugar ABC import subfamilies, (PRU01716-PRU01717) therefore it is not possible to assign their substrate. For those cases a specific annotation is propagated.