HAMAP rule MF_01726
General rule information
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Accession | MF_01726 |
Dates | 3-APR-2007 (Created)
1-JUN-2023 (Last updated, Version 26) |
Name | ABC_ATPase_PotA |
Scope(s) |
Bacteria |
Template(s) | P69874 (POTA_ECOLI); [ Recover all ] |
Triggered by |
PROSITE; PS51305 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | POTA |
Protein name | RecName: Full=Spermidine/putrescine import ATP-binding protein PotA; EC=7.6.2.11; |
Gene name | Name=potA; |
Comments
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FUNCTION | Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. |
CATALYTIC ACTIVITY | Reaction=ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1.; EC=7.6.2.11; |
SUBUNIT | The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). |
case not defined <Property:Membrane> or <Property:Membrane=1> | |
SUBCELLULAR LOCATION | Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2> | |
SUBCELLULAR LOCATION | Cell inner membrane; Peripheral membrane protein. |
end case | |
SIMILARITY | Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. |
Keywords
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ATP-binding | |
case defined <Property:Membrane> and <Property:Membrane=2> | |
Cell inner membrane | |
end case | |
Cell membrane | |
Membrane | |
Nucleotide-binding | |
Transport | |
<a href="https://www.uniprot.org/keywords/KW-1278">Translocase</a> |
Gene Ontology
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GO:0015846; Biological process:polyamine transport |
GO:0015417; Molecular function:ABC-type polyamine transporter activity |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF00005; ABC_tran; 1; |
NCBIfam | TIGR01187; PotA; 1; |
PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
PROSITE | PS50893; ABC_TRANSPORTER_2; 1; |
Features
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Additional information
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Size range | 250-300 amino acids |
Related rules |
PRU01700 |
Fusion | Nter: None Cter: None |