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| Annotation rule MF_01726 |
General rule information
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| Accession | MF_01726 |
| Dates | 3-APR-2007 (Created) 19-NOV-2019 (Last updated, Version 23) |
| Name | ABC_ATPase_PotA |
| Scope | Bacteria |
| Template | P69874 (POTA_ECOLI) |
| Triggered by | PROSITE; PS51305 |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. |
| Catalytic activity | Reaction=ATP + H(2)O + polyamine-[polyamine-binding protein](Side 1) = ADP + phosphate + polyamine(Side 2) + [polyamine-binding protein](Side 1).; EC=7.6.2.11; |
| Subunit | The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). |
case not defined <Property:Membrane> or <Property:Membrane=1>
| Subcellular location | Cell membrane; Peripheral membrane protein. |
else case <Property:Membrane=2>
| Subcellular location | Cell inner membrane; Peripheral membrane protein. |
end case
| Similarity | Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. |
Keywords
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case defined <Property:Membrane> and <Property:Membrane=2>
end case
Gene Ontology
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GO:0015846; Biological process: polyamine transport.
GO:0015417; Molecular function: ATPase-coupled polyamine transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.
GO:0015417; Molecular function: ATPase-coupled polyamine transmembrane transporter activity.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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| Pfam | PF00005; ABC_tran; 1; |
| TIGRFAMs | TIGR01187; PotA; 1; |
| PROSITE | PS00211; ABC_TRANSPORTER_1; 1; |
| PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434; |
Additional information
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| Size range | 250-300 amino acids |
| Related rules | PRU01700 |
| Fusion | None |