HAMAP logo

HAMAP rule MF_01817

Send feedback

General rule information [?]

Accession MF_01817
Dates 17-AUG-2003 (Created)
27-MAR-2023 (Last updated, Version 26)
Name Recomb_XerD_like
Scope(s) Bacteria
Template(s) P0A4T0 (XERDL_STRR6); Q9CG32 (XERDL_LACLA); [ Recover all ]
Triggered by HAMAP; MF_01817 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier XERDL
Protein name RecName: Full=Tyrosine recombinase XerD-like;

Comments [?]

FUNCTIONPutative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
SIMILARITYBelongs to the 'phage' integrase family. XerD-like subfamily.

Keywords [?]

Gene Ontology [?]

GO:0009037; Molecular function:tyrosine-based site-specific recombinase activity
GO:0006310; Biological process:DNA recombination
GO:0006313; Biological process:DNA transposition
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00589; Phage_integrase; 1;
Pfam PF02899; Phage_integr_N; 1;
PROSITE PS51900; CB; 1;

Features [?]

Key From To Description Tag Condition FTGroup
ACT_SITE 236 236 /note="O-(3'-phospho-DNA)-tyrosine intermediate" Y

Additional information [?]

Size range 238-253 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments Although strongly related to XerD, it constitutes a distinct protein family. In contrast to the classic XerD protein, it does not contain the Arg-His-Arg-His (R-H-R-H) sandwich residues that are clustered with the Tyr active site. It also lacks the C-terminal region which is known to mediate the interaction with XerC. It is therefore unknown whether it has tyrosine recombinase activity or acts as a regulator.

View rule in raw text format (no links)