HAMAP rule MF_01817
General rule information
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| Accession | MF_01817 |
| Dates | 17-AUG-2003 (Created) 27-MAR-2023 (Last updated, Version 26) |
| Name | Recomb_XerD_like |
| Scope | Bacteria; Streptococcaceae |
| Templates | P0A4T0 (XERDL_STRR6); Q9CG32 (XERDL_LACLA): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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Comments
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| Function | Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the 'phage' integrase family. XerD-like subfamily. |
Keywords
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Gene Ontology
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GO:0009037; Molecular function: tyrosine-based site-specific recombinase activity.
GO:0006310; Biological process: DNA recombination.
GO:0006313; Biological process: DNA transposition.
GO:0005737; Cellular component: cytoplasm.
GO:0006310; Biological process: DNA recombination.
GO:0006313; Biological process: DNA transposition.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF00589; Phage_integrase; 1; |
| PF02899; Phage_integr_N; 1; | |
| PROSITE | PS51900; CB; 1; trigger=PRU01248; |
| PS51898; TYR_RECOMBINASE; 1; trigger=PRU01246; |
Features
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| From: XERDL_LACLA (Q9CG32) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 236 | 236 | O-(3'-phospho-DNA)-tyrosine intermediate | Y | ||||||||
Additional information
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| Size range | 238-253 amino acids |
| Related rules | None |
| Fusion | None |
| Comments | Although strongly related to XerD, it constitutes a distinct protein family. In contrast to the classic XerD protein, it does not contain the Arg-His-Arg-His (R-H-R-H) sandwich residues that are clustered with the Tyr active site. It also lacks the C-terminal region which is known to mediate the interaction with XerC. It is therefore unknown whether it has tyrosine recombinase activity or acts as a regulator. |