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Annotation rule MF_01818 |
General rule information
[?]
Accession |
MF_01818 |
Dates |
12-DEC-2003 (Created) 19-NOV-2019 (Last updated, Version 23) |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
case <OC:Enterobacterales>
Protein name |
RecName:
|
Full=Ribonuclease BN;
|
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Short=RNase BN;
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EC 3.1.-.-;
|
AltName:
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Full=Ribonuclease Z homolog;
|
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Short=RNase Z homolog;
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|
else
Protein name |
RecName:
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Full=Ribonuclease Z;
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Short=RNase Z;
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EC 3.1.26.11;
|
AltName:
|
Full=tRNA 3 endonuclease;
|
AltName:
|
Full=tRNase Z;
|
|
end case
case <OC:Enterobacterales>
Function |
Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities. |
else
Function |
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. |
Catalytic activity |
Reaction=Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.; EC=3.1.26.11; |
end case
case <FTGroup:1>
Cofactor |
Zn(2+) Note: Binds 2 Zn(2+) ions. |
end case
case <OC:Enterobacterales>
Similarity |
Belongs to the RNase Z family. RNase BN subfamily. |
else
Similarity |
Belongs to the RNase Z family. |
end case
case <OC:Enterobacterales>
end case
case <FTGroup:1>
end case
case <FTGroup:1>
end case
case <OC:Enterobacterales>
GO:0004519; Molecular function: endonuclease activity.
GO:0004527; Molecular function: exonuclease activity.
else
GO:0042781; Molecular function: 3'-tRNA processing endoribonuclease activity.
end case
From: RNZ_BACSU (P54548) |
Key
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From
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To
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Description
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Tag
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|
Condition
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|
FTGroup
|
ACT_SITE
|
|
67
|
|
67
|
|
Proton acceptor
|
|
|
|
D
|
|
|
METAL
|
|
63
|
|
63
|
|
Zinc 1; catalytic
|
|
|
|
H
|
|
1
|
METAL
|
|
65
|
|
65
|
|
Zinc 1; catalytic
|
|
|
|
H
|
|
1
|
METAL
|
|
67
|
|
67
|
|
Zinc 2; catalytic
|
|
|
|
D
|
|
1
|
METAL
|
|
68
|
|
68
|
|
Zinc 2; catalytic
|
|
|
|
H
|
|
1
|
METAL
|
|
140
|
|
140
|
|
Zinc 1; catalytic
|
|
|
|
H
|
|
1
|
METAL
|
|
211
|
|
211
|
|
Zinc 1; catalytic
|
|
|
|
D
|
|
1
|
METAL
|
|
211
|
|
211
|
|
Zinc 2; catalytic
|
|
|
|
D
|
|
1
|
METAL
|
|
269
|
|
269
|
|
Zinc 2; catalytic
|
|
|
|
H
|
|
1
|
Additional information
[?]
Size range |
220-407 amino acids |
Related rules |
None |
Fusion |
Nter: None; Cter: <Unknown> |
Comments |
Was initially thought to be an arylsulfatase, given its similarity with the atsA family. |