HAMAP logo

HAMAP rule MF_01820

Send feedback

General rule information [?]

Accession MF_01820
Dates 30-OCT-2003 (Created)
1-JUN-2023 (Last updated, Version 32)
Name GTPase_RsgA
Scope(s) Bacteria
Template(s) P39286 (RSGA_ECOLI); Q9X242 (RSGA_THEMA); [ Recover all ]
Triggered by HAMAP; MF_01820 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RSGA
Protein name RecName: Full=Small ribosomal subunit biogenesis GTPase RsgA;
Gene name Name=rsgA;

Comments [?]

FUNCTIONOne of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
case <FTGroup:1>
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
end case
SUBUNITMonomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
SIMILARITYBelongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.

Keywords [?]

Gene Ontology [?]

GO:0003924; Molecular function:GTPase activity
GO:0005525; Molecular function:GTP binding
GO:0005737; Cellular component:cytoplasm
GO:0042274; Biological process:ribosomal small subunit biogenesis

Cross-references [?]

Pfam PF03193; DUF258; 1;
NCBIfam TIGR00157; TIGR00157; 1;
PROSITE PS51721; G_CP; 1;

Features [?]

Key From To Description Tag Condition FTGroup
BINDING 160 163 /ligand="GTP"
BINDING 214 222 /ligand="GTP"
BINDING 297 297 /ligand="Zn(2+)"
C 1
BINDING 302 302 /ligand="Zn(2+)"
C 1
BINDING 304 304 /ligand="Zn(2+)"
H 1
BINDING 310 310 /ligand="Zn(2+)"
C 1

Additional information [?]

Size range 272-387 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments In contrast to most P-loop GTPases, which have a G1-G2-G3-G4 pattern of GTP-binding motifs, contains a permuted G4-G1-G2-G3 pattern. Often referred to as YjeQ.

View rule in raw text format (no links)