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Annotation rule MF_01820
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General rule information [?]

Accession MF_01820
Dates 30-OCT-2003 (Created)
12-MAY-2020 (Last updated, Version 29)
Name GTPase_RsgA
Scope
Bacteria
Archaea; Methanosarcinales
Templates P39286 (RSGA_ECOLI); Q9X242 (RSGA_THEMA): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RSGA
Protein name
RecName: Full=Small ribosomal subunit biogenesis GTPase RsgA;
EC 3.6.1.-;
Gene name
rsgA

Comments [?]

Function One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Subunit Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
Subcellular location Cytoplasm.
Similarity Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0003924; Molecular function: GTPase activity.
GO:0005525; Molecular function: GTP binding.
GO:0005737; Cellular component: cytoplasm.
GO:0042274; Biological process: ribosomal small subunit biogenesis.

Cross-references [?]

Pfam PF03193; DUF258; 1;
TIGRFAMs TIGR00157; TIGR00157; 1;
PROSITE PS50936; ENGC_GTPASE; 1;
PS51721; G_CP; 1; trigger=PRU01058;

Features [?]

From: RSGA_SALTY (Q8ZKB0)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     160     163       GTP     [NTSA]-K-x-D  
NP_BIND     214     222       GTP     [AG]-x(4)-G-K-[ST]-[TS]  
METAL     297     297       Zinc     C   1
METAL     302     302       Zinc     C   1
METAL     304     304       Zinc; via pros nitrogen     H   1
METAL     310     310       Zinc     C   1

Additional information [?]

Size range 272-387 amino acids
Related rules None
Fusion None
Comments In contrast to most P-loop GTPases, which have a G1-G2-G3-G4 pattern of GTP-binding motifs, contains a permuted G4-G1-G2-G3 pattern. Often referred to as YjeQ.