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HAMAP rule MF_01840

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General rule information [?]

Accession MF_01840
Dates 28-JUL-2005 (Created)
17-FEB-2023 (Last updated, Version 25)
Name AcsF
Scope
Bacteria
Bacteria; Cyanobacteriota
Bacteria; Alphaproteobacteria
Bacteria; Betaproteobacteria
Plastid
Template P0DJN9 (ACSF_RUBGE)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ACSF
case <OC:Bacteria> and not <OC:Cyanobacteriota>
Protein name
RecName: Full=Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase;
Short=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase;
EC 1.14.13.81;
else case <OC:Cyanobacteriota> or <OG:Chloroplast>
Protein name
RecName: Full=Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase;
Short=Mg-protoporphyrin IX monomethyl ester oxidative cyclase;
EC 1.14.13.81;
else
Protein name
RecName: Full=Probable magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase;
Short=Mg-protoporphyrin IX monomethyl ester oxidative cyclase;
EC 1.14.13.81;
end case
Gene name
acsF

Comments [?]

Function Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME).
Catalytic activity RHEA:33235: 2 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 = 3,8-divinyl protochlorophyllide a + 5 H2O + 3 NADP(+)
EC 1.14.13.81
Cofactor Fe cation
case <OC:Bacteria> and not <OC:Cyanobacteriota>
Pathway Porphyrin-containing compound metabolism; bacteriochlorophyll biosynthesis (light-independent).
end case
case <OC:Cyanobacteriota> or <OG:Chloroplast>
Pathway Porphyrin-containing compound metabolism; chlorophyll biosynthesis (light-independent).
end case
case <OG:Chloroplast>
Subcellular location Plastid, chloroplast.
end case
Similarity Belongs to the AcsF family.

Keywords [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
Bacteriochlorophyll biosynthesis
end case
Chlorophyll biosynthesis
Iron
Metal-binding
NADP
Oxidoreductase
Photosynthesis

Gene Ontology [?]

case <OC:Bacteria> and not <OC:Cyanobacteriota>
GO:0030494; Biological process: bacteriochlorophyll biosynthetic process.
end case
case <OC:Cyanobacteriota> or <OG:Chloroplast>
GO:0015995; Biological process: chlorophyll biosynthetic process.
end case
GO:0005506; Molecular function: iron ion binding.
GO:0048529; Molecular function: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity.
GO:0015979; Biological process: photosynthesis.
case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Cross-references [?]

Pfam PF02915; Rubrerythrin; 1;
TIGRFAMs TIGR02029; AcsF; 1;

Additional information [?]

Size range 299-390 amino acids
Related rules None
Fusion None


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