HAMAP rule MF_01856
General rule information
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Accession | MF_01856 |
Dates | 5-FEB-2009 (Created) 19-NOV-2022 (Last updated, Version 14) |
Name | 16SrRNA_methyltr_B |
Scope | Bacteria; Enterobacterales |
Template | P36929 (RSMB_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. |
Catalytic activity | RHEA:42748: cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.176 |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. |
Keywords
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Gene Ontology
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GO:0016434; Molecular function: rRNA (cytosine) methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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PROSITE | PS01153; NOL1_NOP2_SUN; 1; |
Pfam | PF01189; Nol1_Nop2_Fmu; 1; |
PF01029; NusB; 1; | |
TIGRFAMs | TIGR00563; RsmB; 1; |
PROSITE | PS01153; NOL1_NOP2_SUN; 1; |
PS51686; SAM_MT_RSMB_NOP; 1; |
Features
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From: RSMB_ECOLI (P36929) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 254 | 260 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | [ACSV]-[ACPS]-[AGP]-[PQ]-[AG]-[GINS]-K | ||||||||
ACT_SITE | 375 | 375 | Nucleophile | C | ||||||||
BINDING | 277 | 277 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | D | ||||||||
BINDING | 303 | 303 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | D | ||||||||
BINDING | 322 | 322 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789 | D |
Additional information
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Size range | 422-433 amino acids |
Related rules | None |
Fusion | None |
Comments | The family is restricted to Enterobacterales in order to avoid wrong matches. |