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Annotation rule MF_01856
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General rule information [?]

Accession MF_01856
Dates 5-FEB-2009 (Created)
19-NOV-2019 (Last updated, Version 11)
Name 16SrRNA_methyltr_B
Scope
Bacteria; Enterobacterales
Template P36929 (RSMB_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
RSMB
Protein name
RecName: Full=Ribosomal RNA small subunit methyltransferase B;
EC 2.1.1.176;
AltName: Full=16S rRNA m5C967 methyltransferase;
AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RsmB;
Gene name
rsmB, sun

Comments [?]

Function Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
Catalytic activity RHEA:42748: cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine
EC 2.1.1.176
Subcellular location Cytoplasm.
Similarity Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

Keywords [?]

Cytoplasm
Methyltransferase
RNA-binding
rRNA processing
S-adenosyl-L-methionine
Transferase

Gene Ontology [?]

GO:0016434; Molecular function: rRNA (cytosine) methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS01153; NOL1_NOP2_SUN; 1;
Pfam PF01189; Nol1_Nop2_Fmu; 1;
PF01029; NusB; 1;
TIGRFAMs TIGR00563; RsmB; 1;
PROSITE PS01153; NOL1_NOP2_SUN; 1;
PS51686; SAM_MT_RSMB_NOP; 1;

Features [?]

From: RSMB_ECOLI (P36929)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     254     260       S-adenosyl-L-methionine binding     [ACSV]-[ACPS]-[AGP]-[PQ]-[AG]-[GINS]-K  
ACT_SITE     375     375       Nucleophile     C  
BINDING     277     277       S-adenosyl-L-methionine     D  
BINDING     303     303       S-adenosyl-L-methionine     D  
BINDING     322     322       S-adenosyl-L-methionine     D  

Additional information [?]

Size range 422-433 amino acids
Related rules None
Fusion None
Comments The family is restricted to Enterobacterales in order to avoid wrong matches.


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