HAMAP rule MF_01857

General rule information [?]

Accession	MF_01857
Dates	6-FEB-2009 (Created) 19-NOV-2019 (Last updated, Version 8)

Name	23SrRNA_methyltr_I

Scope

Bacteria; Gammaproteobacteria

Template

P75876 (RLMI_ECOLI)

Triggered by

HAMAP; MF_01857 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RLMI

Protein name

RecName:		Full=Ribosomal RNA large subunit methyltransferase I;
		EC 2.1.1.191;
AltName:		Full=23S rRNA m5C1962 methyltransferase;
AltName:		Full=rRNA (cytosine-C(5)-)-methyltransferase RlmI;

Gene name

rlmI

Comments [?]

Function	Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
Catalytic activity	RHEA:42912: cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine EC 2.1.1.191
Subcellular location	Cytoplasm.
Similarity	Belongs to the methyltransferase superfamily. RlmI family.

Keywords [?]

Cytoplasm
Methyltransferase
RNA-binding
rRNA processing
S-adenosyl-L-methionine
Transferase

Gene Ontology [?]

GO:0016434; Molecular function: rRNA (cytosine) methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS50890; PUA; 1; trigger=PRU00161;
Pfam	PF03602; Cons_hypoth95; 1;

Additional information [?]

Size range	394-403 amino acids
Related rules	None
Fusion	None
Comments	The family is restricted to Gammaproteobacteria in order to avoid wrong matches.

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