HAMAP rule MF_01857
General rule information
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| Accession | MF_01857 |
| Dates | 6-FEB-2009 (Created)
19-NOV-2019 (Last updated, Version 8) |
| Name | 23SrRNA_methyltr_I |
| Scope(s) |
Bacteria Gammaproteobacteria |
| Template(s) | P75876 (RLMI_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_01857 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RLMI |
| Protein name | RecName: Full=Ribosomal RNA large subunit methyltransferase I; EC=2.1.1.191; AltName: Full=23S rRNA m5C1962 methyltransferase; AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RlmI; |
| Gene name | Name=rlmI; |
Comments
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| FUNCTION | Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. |
| CATALYTIC ACTIVITY | Reaction=cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5- methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42912, Rhea:RHEA-COMP:10382, Rhea:RHEA-COMP:10386, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; EC=2.1.1.191; |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the methyltransferase superfamily. RlmI family. |
Keywords
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Gene Ontology
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| GO:0016434; Molecular function:rRNA (cytosine) methyltransferase activity |
| GO:0031167; Biological process:rRNA methylation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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Additional information
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| Size range | 394-403 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | The family is restricted to Gammaproteobacteria in order to avoid wrong matches. |