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HAMAP rule MF_01857

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General rule information [?]

Accession MF_01857
Dates 6-FEB-2009 (Created)
19-NOV-2019 (Last updated, Version 8)
Name 23SrRNA_methyltr_I
Bacteria; Gammaproteobacteria
Template P75876 (RLMI_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Ribosomal RNA large subunit methyltransferase I;
AltName: Full=23S rRNA m5C1962 methyltransferase;
AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RlmI;
Gene name

Comments [?]

Function Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
Catalytic activity RHEA:42912: cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
Subcellular location Cytoplasm.
Similarity Belongs to the methyltransferase superfamily. RlmI family.

Keywords [?]

Gene Ontology [?]

GO:0016434; Molecular function: rRNA (cytosine) methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS50890; PUA; 1; trigger=PRU00161;
Pfam PF03602; Cons_hypoth95; 1;

Additional information [?]

Size range 394-403 amino acids
Related rules None
Fusion None
Comments The family is restricted to Gammaproteobacteria in order to avoid wrong matches.