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HAMAP rule MF_01857

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General rule information [?]

Accession MF_01857
Dates 6-FEB-2009 (Created)
19-NOV-2019 (Last updated, Version 8)
Name 23SrRNA_methyltr_I
Scope(s) Bacteria
Template(s) P75876 (RLMI_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01857 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RLMI
Protein name RecName: Full=Ribosomal RNA large subunit methyltransferase I;
AltName: Full=23S rRNA m5C1962 methyltransferase;
AltName: Full=rRNA (cytosine-C(5)-)-methyltransferase RlmI;
Gene name Name=rlmI;

Comments [?]

FUNCTIONSpecifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
CATALYTIC ACTIVITY Reaction=cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine = 5- methylcytidine(1962) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42912, Rhea:RHEA-COMP:10382, Rhea:RHEA-COMP:10386, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74483, ChEBI:CHEBI:82748; EC=;
SIMILARITYBelongs to the methyltransferase superfamily. RlmI family.

Keywords [?]

Gene Ontology [?]

GO:0016434; Molecular function:rRNA (cytosine) methyltransferase activity
GO:0031167; Biological process:rRNA methylation
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS50890; PUA; 1;
Pfam PF03602; Cons_hypoth95; 1;

Features [?]

Additional information [?]

Size range 394-403 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments The family is restricted to Gammaproteobacteria in order to avoid wrong matches.

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