HAMAP rule MF_01858
General rule information
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Accession | MF_01858 |
Dates | 9-FEB-2009 (Created) 19-NOV-2019 (Last updated, Version 14) |
Name | 23SrRNA_methyltr_KL |
Scope | Bacteria |
Template | P75864 (RLMKL_ECOLI) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. |
Catalytic activity | RHEA:42740: guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine
EC 2.1.1.173 |
RHEA:43772: guanosine(2069) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2069) in 23S rRNA + S-adenosyl-L-homocysteine
EC 2.1.1.264 |
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Subcellular location | Cytoplasm. |
Similarity | Belongs to the methyltransferase superfamily. RlmKL family. |
Keywords
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Gene Ontology
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GO:0052915; Molecular function: 23S rRNA (guanine(2445)-N(2))-methyltransferase activity.
GO:0070043; Molecular function: rRNA (guanine-N7-)-methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
GO:0070043; Molecular function: rRNA (guanine-N7-)-methyltransferase activity.
GO:0031167; Biological process: rRNA methylation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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PROSITE | PS51165; THUMP; 1; trigger=PRU00529; |
PS01261; UPF0020; 1; | |
Pfam | PF03602; Cons_hypoth95; 0-1; |
PF02926; THUMP; 1; | |
PF01170; UPF0020; 1; | |
PIRSF | PIRSF037618; RNA_Mtase_bacteria_prd; 1; |
Additional information
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Size range | 676-807 amino acids |
Related rules | None |
Fusion | None |