HAMAP rule MF_01872

General rule information [?]

Accession	MF_01872
Dates	29-SEP-2009 (Created) 19-NOV-2019 (Last updated, Version 8)

Name	tRNA_methyltr_YfiC

Scope

Bacteria

Template

P31825 (TRMN6_ECOLI)

Triggered by

HAMAP; MF_01872 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

TRMN6

Protein name

RecName:		Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase;
		EC 2.1.1.223;
AltName:		Full=tRNA m6A37 methyltransferase;

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>

Gene name

yfiC

end case

Comments [?]

Function	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
Catalytic activity	RHEA:43160: adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine EC 2.1.1.223
Subcellular location	Cytoplasm.
Similarity	Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.

Keywords [?]

Cytoplasm
Methyltransferase
S-adenosyl-L-methionine
Transferase
tRNA processing

Gene Ontology [?]

GO:0016430; Molecular function: tRNA (adenine-N6-)-methyltransferase activity.
GO:0008033; Biological process: tRNA processing.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE	PS00092; N6_MTASE; 1;
Pfam	PF05175; MTS; 1;
	PF08241; Methyltransf_11; 1;
PRINTS	PR00507; N12N6MTFRASE; 1;

Additional information [?]

Size range	231-265 amino acids
Related rules	None
Fusion	None

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