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HAMAP rule MF_01872

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General rule information [?]

Accession MF_01872
Dates 29-SEP-2009 (Created)
13-OCT-2023 (Last updated, Version 9)
Name tRNA_methyltr_YfiC
Scope(s) Bacteria
Template(s) P31825 (TRMN6_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01872 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TRMN6
Protein name RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase;
                 EC=2.1.1.223;
AltName: Full=tRNA m6A37 methyltransferase;
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Gene name Name=yfiC;
end case

Comments [?]

FUNCTIONSpecifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
CATALYTIC ACTIVITY Reaction=adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:43160, Rhea:RHEA-COMP:10369, Rhea:RHEA-COMP:10370, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.223;
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.

Keywords [?]


Gene Ontology [?]

GO:0016430; Molecular function:tRNA (adenine-N6)-methyltransferase activity
GO:0008033; Biological process:tRNA processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS00092; N6_MTASE; 1;
Pfam PF05175; MTS; 1;
Pfam PF08241; Methyltransf_11; 1;
PRINTS PR00507; N12N6MTFRASE; 1;

Features [?]


Additional information [?]

Size range 231-265 amino acids
Related rules None
Fusion Nter: None Cter: None



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