HAMAP rule MF_01872

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_01872
Accession	MF_01872
Dates	29-SEP-2009 (Created) 02-SEP-2024 (Last updated, Version 11)
Name	tRNA_methyltr_YfiC
Scope(s)	Bacteria
Template(s)	P31825; [ Recover all ]
Triggered by	HAMAP; MF_01872 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TRMN6
Protein name	RecName: Full=tRNA1(Val) (adenine(37)-N6)-methyltransferase; EC=2.1.1.223; AltName: Full=tRNA m6A37 methyltransferase;
case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
Gene name	Name=yfiC;
end case

Comments [?]

FUNCTION	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
CATALYTIC ACTIVITY	Reaction=adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = N(6)- methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine + H(+); Xref=Rhea:RHEA:43160, Rhea:RHEA-COMP:10369, Rhea:RHEA-COMP:10370, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74411, ChEBI:CHEBI:74449; EC=2.1.1.223;
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.

Keywords [?]

Gene Ontology [?]

GO:0016430; Molecular function:tRNA (adenine-N6)-methyltransferase activity

GO:0008033; Biological process:tRNA processing

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]