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Annotation rule MF_01884
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General rule information [?]

Accession MF_01884
Dates 4-AUG-2010 (Created)
19-NOV-2019 (Last updated, Version 10)
Name Rho
Template P0AG30 (RHO_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Transcription termination factor Rho;
EC 3.6.4.-;
AltName: Full=ATP-dependent helicase Rho;
Gene name

Comments [?]

Function Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
Subunit Homohexamer. The homohexamer assembles into an open ring structure.
Similarity Belongs to the Rho family.

Keywords [?]

Gene Ontology [?]

GO:0005524; Molecular function: ATP binding.
GO:0004386; Molecular function: helicase activity.
GO:0003723; Molecular function: RNA binding.
GO:0006353; Biological process: DNA-templated transcription, termination.

Cross-references [?]

Pfam PF00006; ATP-synt_ab; 1;
PF07498; Rho_N; 1;
PF07497; Rho_RNA_bind; 1;
TIGRFAMs TIGR00767; Rho; 1;
PROSITE PS51856; RHO_RNA_BD; 1; trigger=PRU01203;

Features [?]

From: RHO_ECOLI (P0AG30)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     169     174       ATP     G-x-G-x-x-[GAS]  
NP_BIND     181     186       ATP     [KR]-x-G-K-[TS]-x  
REGION (Optional)     61     66       RNA-binding 1     G-[FY]-G-[FYR]-[LV]-R   1
REGION (Optional)     78     80       RNA-binding 1     D-I-[YFR]   1
REGION (Optional)     108     110       RNA-binding 1     [ED]-R-[YFR]   1
REGION (Optional)     284     288       RNA-binding 2     [VL]-L-[TS]-G-G   1
BINDING     212     212       ATP     R  
SITE (Optional)     326     326       RNA-binding 2     K   1

Additional information [?]

Size range 341-849 amino acids
Related rules None
Fusion None