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Annotation rule MF_01891
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General rule information [?]

Accession MF_01891
Dates 14-FEB-2011 (Created)
19-NOV-2019 (Last updated, Version 8)
Name FhlC
Scope
Bacteria; Proteobacteria
Template P0ABY7 (FLHC_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FLHC
Protein name
RecName: Full=Flagellar transcriptional regulator FlhC;
Gene name
flhC

Comments [?]

Function Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
case <FTGroup:1>
Cofactor Zn(2+)
Note: Binds 1 zinc ion per subunit.
end case
Subunit Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
Subcellular location Cytoplasm.
Similarity Belongs to the FlhC family.

Keywords [?]

case <FTGroup:1>
end case

Gene Ontology [?]

GO:0003677; Molecular function: DNA binding.
case <FTGroup:1>
GO:0008270; Molecular function: zinc ion binding.
end case
GO:0006355; Biological process: regulation of transcription, DNA-templated.
GO:1902208; Biological process: regulation of bacterial-type flagellum assembly.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF05280; FlhC; 1;
PIRSF PIRSF003159; FlhC; 1;

Features [?]

From: FLHC_ECOLI (P0ABY7)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     137     137       Zinc     C   1
METAL     140     140       Zinc     C   1
METAL     157     157       Zinc     C   1
METAL     160     160       Zinc     C   1

Additional information [?]

Size range 169-225 amino acids
Related rules None
Fusion None