HAMAP rule MF_01892

General rule information [?]

Accession	MF_01892
Dates	2-MAR-2011 (Created) 19-NOV-2019 (Last updated, Version 6)

Name	tRNA_Ile2_agm2C_synt

Scope

Archaea

Template

O28025 (TIAS_ARCFU)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

TIAS

Protein name

RecName:		Full=tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS;
		Short=tRNA(Ile2)-agm2C synthetase;
		EC 6.3.4.22;
AltName:		Full=tRNA(Ile2) agmatidine synthetase;

Gene name

tiaS

Comments [?]

Function	ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
Catalytic activity	RHEA:43608: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate EC 6.3.4.22
Subcellular location	Cytoplasm.
Similarity	Belongs to the TiaS family.

Keywords [?]

Gene Ontology [?]

GO:0016879; Molecular function: ligase activity, forming carbon-nitrogen bonds.
GO:0002101; Biological process: tRNA wobble cytosine modification.

Cross-references [?]

Pfam	PF08489; DUF1743; 1;
	PF01336; tRNA_anti; 0-1; trigger=Yes;

Additional information [?]