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HAMAP rule MF_01892

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General rule information [?]

Accession MF_01892
Dates 2-MAR-2011 (Created)
19-NOV-2019 (Last updated, Version 6)
Name tRNA_Ile2_agm2C_synt
Scope(s) Archaea
Template(s) O28025 (TIAS_ARCFU); [ Recover all ]
Triggered by HAMAP; MF_01892 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TIAS
Protein name RecName: Full=tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS;
                 Short=tRNA(Ile2)-agm2C synthetase;
AltName: Full=tRNA(Ile2) agmatidine synthetase;
Gene name Name=tiaS;

Comments [?]

FUNCTIONATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
CATALYTIC ACTIVITY Reaction=agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2- agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate; Xref=Rhea:RHEA:43608, Rhea:RHEA-COMP:10625, Rhea:RHEA-COMP:10626, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58145, ChEBI:CHEBI:82748, ChEBI:CHEBI:83545, ChEBI:CHEBI:456215; EC=;
SIMILARITYBelongs to the TiaS family.

Keywords [?]

Gene Ontology [?]

GO:0016879; Molecular function:ligase activity, forming carbon-nitrogen bonds
GO:0002101; Biological process:tRNA wobble cytosine modification

Cross-references [?]

Pfam PF08489; DUF1743; 1;
Pfam PF01336; tRNA_anti; 0-1;

Features [?]

Additional information [?]

Size range 397-508 amino acids
Related rules None
Fusion Nter: None Cter: None

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