HAMAP logo

HAMAP rule MF_01892

Send feedback

General rule information [?]

Accession MF_01892
Dates 2-MAR-2011 (Created)
19-NOV-2019 (Last updated, Version 6)
Name tRNA_Ile2_agm2C_synt
Template O28025 (TIAS_ARCFU)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS;
Short=tRNA(Ile2)-agm2C synthetase;
AltName: Full=tRNA(Ile2) agmatidine synthetase;
Gene name

Comments [?]

Function ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
Catalytic activity RHEA:43608: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate
Subcellular location Cytoplasm.
Similarity Belongs to the TiaS family.

Keywords [?]

Gene Ontology [?]

GO:0016879; Molecular function: ligase activity, forming carbon-nitrogen bonds.
GO:0002101; Biological process: tRNA wobble cytosine modification.

Cross-references [?]

Pfam PF08489; DUF1743; 1;
PF01336; tRNA_anti; 0-1; trigger=Yes;

Additional information [?]

Size range 397-508 amino acids
Related rules None
Fusion None