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Annotation rule MF_01916 |
General rule information
[?]
Accession |
MF_01916 |
Dates |
15-APR-2014 (Created) 19-NOV-2019 (Last updated, Version 5) |
Name |
Cardiolipin_synth_Cls |
Propagated annotation
[?]
Identifier, protein and gene names
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Protein name |
RecName:
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Full=Cardiolipin synthase;
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Short=CL synthase;
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EC 2.7.8.-;
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Function |
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. |
Catalytic activity |
RHEA:31451: 2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol
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case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Multi-pass membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Multi-pass membrane protein. |
end case
Similarity |
Belongs to the phospholipase D family. Cardiolipin synthase subfamily. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0016780; Molecular function: phosphotransferase activity, for other substituted phosphate groups.
GO:0008654; Biological process: phospholipid biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
General |
Transmembrane; -; 2-3; trigger=yes; |
From: CLSA_BACSU (P71040) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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222
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222
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H
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ACT_SITE
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224
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224
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K
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ACT_SITE
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229
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229
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D
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ACT_SITE
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400
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400
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H
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ACT_SITE
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402
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402
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K
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ACT_SITE
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407
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407
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D
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Additional information
[?]
Size range |
440-550 amino acids |
Related rules |
None |
Fusion |
None |