Home  |  Contact
Annotation rule MF_01927
Send feedback

General rule information [?]

Accession MF_01927
Dates 10-JUL-2014 (Created)
19-NOV-2019 (Last updated, Version 4)
Name PurU
Scope
Bacteria
Template P37051 (PURU_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
PURU
Protein name
RecName: Full=Formyltetrahydrofolate deformylase;
EC 3.5.1.10;
AltName: Full=Formyl-FH(4) hydrolase;
Gene name
purU

Comments [?]

Function Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
Catalytic activity RHEA:19833: (6S)-10-formyltetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+)
EC 3.5.1.10
Pathway Purine metabolism; IMP biosynthesis via de novo pathway; formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1.
Similarity Belongs to the PurU family.

Keywords [?]


Gene Ontology [?]

GO:0008864; Molecular function: formyltetrahydrofolate deformylase activity.
GO:0006189; Biological process: 'de novo' IMP biosynthetic process.

Cross-references [?]

PROSITE PS51671; ACT; 1; trigger=PRU01007;
Pfam PF01842; ACT; 1;
PF00551; Formyl_trans_N; 1;
PRINTS PR01575; FFH4HYDRLASE; 1;
TIGRFAMs TIGR00655; PurU; 1;
PIRSF PIRSF036480; FormyFH4_hydr; 1;

Features [?]

From: PURU_ECOLI (P37051)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     225     225             D  

Additional information [?]

Size range 230-340 amino acids
Related rules None
Fusion None