HAMAP rule MF_01938
General rule information
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Accession | MF_01938 |
Dates | 28-OCT-2014 (Created) 17-FEB-2023 (Last updated, Version 6) |
Name | MenA_2 |
Scope | Bacteria; Cyanobacteriota |
Template | P73962 (MENA_SYNY3) |
Triggered by |
Propagated annotation
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Identifier, protein and gene names
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Identifier |
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Protein name |
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Gene name |
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Comments
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Function | Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone. |
Catalytic activity | RHEA:47740: 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + demethylphylloquinone + diphosphate
EC 2.5.1.130 |
Pathway | Cofactor biosynthesis; phylloquinone biosynthesis. |
Subcellular location | Cell inner membrane; Multi-pass membrane protein. |
Similarity | Belongs to the MenA family. Type 2 subfamily. |
Keywords
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Gene Ontology
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GO:0016765; Molecular function: transferase activity, transferring alkyl or aryl (other than methyl) groups.
GO:0042372; Biological process: phylloquinone biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
GO:0042372; Biological process: phylloquinone biosynthetic process.
GO:0005886; Cellular component: plasma membrane.
Cross-references
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Pfam | PF01040; UbiA; 1; |
TIGRFAMs | TIGR02235; menA_cyano-plnt; 1; |
PIRSF | PIRSF005355; UBIAD1; 1; |
Computed features
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General | Transmembrane; -; 7-9; trigger=yes; |
Additional information
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Size range | 277-340 amino acids |
Related rules | None |
Fusion | None |