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Annotation rule MF_01938
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General rule information [?]

Accession MF_01938
Dates 28-OCT-2014 (Created)
19-NOV-2019 (Last updated, Version 4)
Name MenA_2
Scope
Bacteria; Cyanobacteria
Template P73962 (MENA_SYNY3)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MENA
Protein name
RecName: Full=2-carboxy-1,4-naphthoquinone phytyltransferase;
EC 2.5.1.130;
AltName: Full=1,4-dihydroxy-2-naphthoate phytyltransferase;
Short=DHNA phytyltransferase;
Gene name
menA

Comments [?]

Function Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4-naphthoquinone.
Catalytic activity RHEA:47740: 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + demethylphylloquinone + diphosphate
EC 2.5.1.130
Pathway Cofactor biosynthesis; phylloquinone biosynthesis.
Subcellular location Cell inner membrane; Multi-pass membrane protein.
Similarity Belongs to the MenA family. Type 2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0016765; Molecular function: transferase activity, transferring alkyl or aryl (other than methyl) groups.
GO:0042372; Biological process: phylloquinone biosynthetic process.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF01040; UbiA; 1;
TIGRFAMs TIGR02235; menA_cyano-plnt; 1;
PIRSF PIRSF005355; UBIAD1; 1;

Computed features [?]

General Transmembrane; -; 7-9; trigger=yes;

Additional information [?]

Size range 277-340 amino acids
Related rules None
Fusion None