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HAMAP rule MF_01952

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General rule information [?]

Accession MF_01952
Dates 6-APR-2006 (Created)
19-NOV-2022 (Last updated, Version 23)
Name UlaF
Scope(s) Bacteria
Template(s) P39306 (ULAF_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01952 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ULAF
case <FTGroup:1>
Protein name RecName: Full=L-ribulose-5-phosphate 4-epimerase UlaF;
AltName: Full=L-ascorbate utilization protein F;
AltName: Full=Phosphoribulose isomerase;
end case
case not <FTGroup:1>
Protein name RecName: Full=Putative L-ribulose-5-phosphate 4-epimerase;
end case
Gene name Name=ulaF;

Comments [?]

FUNCTIONCatalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization.
CATALYTIC ACTIVITY Reaction=L-ribulose 5-phosphate = D-xylulose 5-phosphate; Xref=Rhea:RHEA:22368, ChEBI:CHEBI:57737, ChEBI:CHEBI:58226; EC=;
COFACTOR Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 1 zinc ion per subunit.;
PATHWAYCofactor degradation; L-ascorbate degradation; D-xylulose 5- phosphate from L-ascorbate: step 4/4.
INDUCTIONInduced by L-ascorbate. Repressed by UlaR.
SIMILARITYBelongs to the aldolase class II family. AraD/FucA subfamily.

Keywords [?]

Gene Ontology [?]

GO:0019852; Biological process:L-ascorbic acid metabolic process
GO:0008742; Molecular function:L-ribulose-phosphate 4-epimerase activity
GO:0008270; Molecular function:zinc ion binding

Cross-references [?]

Pfam PF00596; Aldolase_II; 1;

Features [?]

From: ULAF_ECOLI (P39306)
Key From To Description Tag Condition FTGroup
BINDING 26 27 /ligand="substrate" G-N
BINDING 43 44 /ligand="substrate" [TS]-G
BINDING 72 73 /ligand="substrate" S-S
ACT_SITE 118 118 /note="Proton donor/acceptor" D
ACT_SITE 225 225 /note="Proton donor/acceptor" Y
BINDING 74 74 /ligand="Zn(2+)"
D 1
BINDING 93 93 /ligand="Zn(2+)"
H 1
BINDING 95 95 /ligand="Zn(2+)"
H 1
BINDING 167 167 /ligand="Zn(2+)"
H 1

Additional information [?]

Size range 228-228 amino acids
Related rules None
Fusion Nter: None Cter: None

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