HAMAP rule MF_01957
General rule information
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| Accession | MF_01957 |
| Dates | 17-MAY-2006 (Created)
17-FEB-2023 (Last updated, Version 16) |
| Name | PknD_kinase |
| Scope(s) |
Bacteria Chlamydiota |
| Template(s) | P0DPS9 (PKND_CHLT2); [ Recover all ] |
| Triggered by |
HAMAP; MF_01957 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PKND |
| Protein name | RecName: Full=Serine/threonine-protein kinase PknD; EC=2.7.11.1; |
| Gene name | Name=pknD; |
Comments
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| FUNCTION | Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth. |
| CATALYTIC ACTIVITY | Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| CATALYTIC ACTIVITY | Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.1; |
| PTM | Autophosphorylated on serine and threonine residues. |
| SIMILARITY | Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. |
Keywords
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Gene Ontology
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| GO:0004674; Molecular function:protein serine/threonine kinase activity |
Cross-references
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| PROSITE | PS00107; PROTEIN_KINASE_ATP; 1; |
| PROSITE | PS00108; PROTEIN_KINASE_ST; 1; |
| PROSITE | PS50011; PROTEIN_KINASE_DOM; 1; |
| Pfam | PF00069; Pkinase; 1; |
Features
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| From: PKND_CHLTR (P0DPS8) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DOMAIN | 4 | 296 | /note="Protein kinase" | |||||||||
| BINDING | 10 | 18 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
[IV]-G-[KR]-G-G-M-G-[ED]-[VI] | ||||||||
| ACT_SITE | 138 | 138 | /note="Proton acceptor" | D | ||||||||
| BINDING | 33 | 33 | /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616" |
K | ||||||||
Additional information
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| Size range | 910-982 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |