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HAMAP rule MF_01958

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General rule information [?]

Accession MF_01958
Dates 22-MAY-2006 (Created)
19-NOV-2019 (Last updated, Version 14)
Name Acetyl_esterase
Scope
Bacteria; Enterobacterales
Template P23872 (AES_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
AES
Protein name
RecName: Full=Acetyl esterase;
EC 3.1.1.-;
Gene name
aes

Comments [?]

Function Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity.
Subunit Homodimer. Interacts with MalT and MelA.
Subcellular location Cytoplasm.
Similarity Belongs to the 'GDXG' lipolytic enzyme family.

Keywords [?]

Cytoplasm
Hydrolase
Serine esterase

Gene Ontology [?]

GO:0052689; Molecular function: carboxylic ester hydrolase activity.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS01173; LIPASE_GDXG_HIS; 1;
PS01174; LIPASE_GDXG_SER; 1;
Pfam PF07859; Abhydrolase_3; 1;

Features [?]

From: AES_ECOLI (P23872)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     165     165             S  
ACT_SITE     262     262             D  
ACT_SITE     292     292             H  

Additional information [?]

Size range 272-323 amino acids
Related rules None
Fusion None


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