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Annotation rule MF_01961 |
General rule information
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Accession |
MF_01961 |
Dates |
23-OCT-2008 (Created) 19-NOV-2019 (Last updated, Version 24) |
Scope |
Bacteria
Archaea; Euryarchaeota |
case <OC:Bacteria> or <OC:Archaea>
end case
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Catalase-peroxidase;
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Short=CP;
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EC 1.11.1.21;
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AltName:
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Full=Peroxidase/catalase;
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Function |
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. |
Catalytic activity |
RHEA:30275: AH2 + H2O2 = A + 2 H2O
EC 1.11.1.21
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RHEA:20309: 2 H2O2 = 2 H2O + O2
EC 1.11.1.21
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Cofactor |
heme b Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer. |
Subunit |
Homodimer or homotetramer. |
Ptm |
Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. |
Similarity |
Belongs to the peroxidase family. Peroxidase/catalase subfamily. |
GO:0004096; Molecular function: catalase activity.
GO:0004601; Molecular function: peroxidase activity.
General |
Signal; -; 0-1; trigger=yes; |
From: KATG_ECOLI (P13029) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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ACT_SITE
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106
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106
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Proton acceptor
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H
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METAL
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267
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267
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Iron (heme axial ligand)
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H
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SITE
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102
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102
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Transition state stabilizer
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R
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CROSSLNK
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105
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226
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Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with #{Met-252})
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W-x*-Y
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CROSSLNK
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226
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252
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Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with #{Trp-105})
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Y-x*-M
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Additional information
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Size range |
699-781 amino acids |
Related rules |
None |
Fusion |
None |