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Annotation rule MF_02019 |
Accession | MF_02019 |
Dates | 16-FEB-2015 (Created) 20-NOV-2019 (Last updated, Version 3) |
Name | MurF |
Scope | Bacteria |
Template | P11880 (MURF_ECOLI) |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. |
Catalytic activity | RHEA:16085: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine
EC 6.3.2.10 |
Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the MurCDEF family. MurF subfamily. |
Pfam | PF01225; Mur_ligase; 1; |
PF02875; Mur_ligase_C; 1; | |
PF08245; Mur_ligase_M; 1; | |
TIGRFAMs | TIGR01143; murF; 1; |
From: MURF_ECOLI (P11880) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
NP_BIND | 107 | 113 | ATP | G-[ST]-x-G-K-T-[ST] |
Size range | 420-535 amino acids |
Related rules | None |
Fusion | None |