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HAMAP rule MF_02026

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General rule information [?]

Accession MF_02026
Dates 21-APR-2015 (Created)
1-JUN-2023 (Last updated, Version 7)
Name WecE_RffA
Bacteria; Enterobacterales
Template P27833 (WECE_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=dTDP-4-amino-4,6-dideoxygalactose transaminase;
Gene name

Comments [?]

Function Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate.
Catalytic activity RHEA:10368: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate
Cofactor pyridoxal 5'-phosphate
Pathway Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Similarity Belongs to the DegT/DnrJ/EryC1 family.

Keywords [?]

Gene Ontology [?]

GO:0019180; Molecular function: dTDP-4-amino-4,6-dideoxygalactose transaminase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.

Cross-references [?]

Pfam PF01041; DegT_DnrJ_EryC1; 1;
NCBIfam TIGR02379; ECA_wecE; 1;
PIRSF PIRSF000390; PLP_StrS; 1;

Features [?]

From: WECE_ECOLI (P27833)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     181     181       N6-(pyridoxal phosphate)lysine     K  

Additional information [?]

Size range 360-392 amino acids
Related rules None
Fusion None