HAMAP rule MF_02026
General rule information
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| Accession | MF_02026 |
| Dates | 21-APR-2015 (Created) 1-JUN-2023 (Last updated, Version 7) |
| Name | WecE_RffA |
| Scope | Bacteria; Enterobacterales |
| Template | P27833 (WECE_ECOLI) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D-galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D-Glc4O) and L-glutamate. |
| Catalytic activity | RHEA:10368: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate
EC 2.6.1.59 |
| Cofactor | pyridoxal 5'-phosphate |
| Pathway | Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis. |
| Similarity | Belongs to the DegT/DnrJ/EryC1 family. |
Keywords
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Gene Ontology
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GO:0019180; Molecular function: dTDP-4-amino-4,6-dideoxygalactose transaminase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0030170; Molecular function: pyridoxal phosphate binding.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
Cross-references
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| Pfam | PF01041; DegT_DnrJ_EryC1; 1; |
| NCBIfam | TIGR02379; ECA_wecE; 1; |
| PIRSF | PIRSF000390; PLP_StrS; 1; |
Features
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| From: WECE_ECOLI (P27833) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 181 | 181 | N6-(pyridoxal phosphate)lysine | K | ||||||||
Additional information
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| Size range | 360-392 amino acids |
| Related rules | None |
| Fusion | None |