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HAMAP rule MF_02026

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General rule information [?]

Accession MF_02026
Dates 21-APR-2015 (Created)
1-JUN-2023 (Last updated, Version 7)
Name WecE_RffA
Scope(s) Bacteria
Enterobacterales
Template(s) P27833 (WECE_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02026 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier WECE
Protein name RecName: Full=dTDP-4-amino-4,6-dideoxygalactose transaminase;
                 EC=2.6.1.59;
Gene name Name=wecE;

Comments [?]

FUNCTIONCatalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate.
CATALYTIC ACTIVITY Reaction=2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate; Xref=Rhea:RHEA:10368, ChEBI:CHEBI:16810, ChEBI:CHEBI:29985, ChEBI:CHEBI:57649, ChEBI:CHEBI:68492; EC=2.6.1.59;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
PATHWAYBacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
SIMILARITYBelongs to the DegT/DnrJ/EryC1 family.

Keywords [?]


Gene Ontology [?]

GO:0019180; Molecular function:dTDP-4-amino-4,6-dideoxygalactose transaminase activity
GO:0030170; Molecular function:pyridoxal phosphate binding
GO:0009246; Biological process:enterobacterial common antigen biosynthetic process

Cross-references [?]

Pfam PF01041; DegT_DnrJ_EryC1; 1;
NCBIfam TIGR02379; ECA_wecE; 1;
PIRSF PIRSF000390; PLP_StrS; 1;

Features [?]

From: WECE_ECOLI (P27833)
Key From To Description Tag Condition FTGroup
MOD_RES 181 181 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 360-392 amino acids
Related rules None
Fusion Nter: None Cter: None



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