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Annotation rule MF_02027
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General rule information [?]

Accession MF_02027
Dates 22-APR-2015 (Created)
20-NOV-2019 (Last updated, Version 4)
Name WecD_RffC
Scope
Bacteria; Enterobacterales
Template Q8FBQ3 (WECD_ECOL6)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
WECD
Protein name
RecName: Full=dTDP-fucosamine acetyltransferase;
EC 2.3.1.210;
AltName: Full=TDP-fucosamine acetyltransferase;
AltName: Full=dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;
Gene name
wecD

Comments [?]

Function Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA).
Catalytic activity RHEA:34443: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + H(+)
EC 2.3.1.210
Pathway Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Subunit Homodimer.
Similarity Belongs to the WecD family.

Keywords [?]


Gene Ontology [?]

GO:0016747; Molecular function: transferase activity, transferring acyl groups other than amino-acyl groups.
GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.

Cross-references [?]

PROSITE PS51186; GNAT; 1; trigger=PRU00532;
Pfam PF00583; Acetyltransf_1; 1;
TIGRFAMs TIGR02382; wecD_rffC; 1;

Features [?]

From: WECD_ECOL6 (Q8FBQ3)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     168     174       Acetyl-CoA binding        
ACT_SITE     208     208       Proton donor     Y  
BINDING     201     201       Acetyl-CoA     N  
BINDING     207     207       Acetyl-CoA     R  

Additional information [?]

Size range 180-260 amino acids
Related rules None
Fusion None