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Annotation rule MF_02032
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General rule information [?]

Accession MF_02032
Dates 26-MAY-2015 (Created)
20-NOV-2019 (Last updated, Version 4)
Name Tartronate_sem_reduc
Scope
Bacteria; Gammaproteobacteria
Template P0ABQ2 (GARR_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GARR
Protein name
RecName: Full=2-hydroxy-3-oxopropionate reductase;
EC 1.1.1.60;
AltName: Full=Tartronate semialdehyde reductase;
Short=TSAR;
Gene name
garR

Comments [?]

Function Catalyzes the reduction of tatronate semialdehyde to D-glycerate.
Catalytic activity RHEA:18841: (R)-glycerate + NADP(+) = 2-hydroxy-3-oxopropanoate + H(+) + NADPH
EC 1.1.1.60
RHEA:18845: (R)-glycerate + NAD(+) = 2-hydroxy-3-oxopropanoate + H(+) + NADH
EC 1.1.1.60
Pathway Carbohydrate acid metabolism; galactarate degradation; D-glycerate from galactarate: step 3/3.
Similarity Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008679; Molecular function: 2-hydroxy-3-oxopropionate reductase activity.
GO:0046392; Biological process: galactarate catabolic process.

Cross-references [?]

PROSITE PS00895; 3_HYDROXYISOBUT_DH; 1;
Pfam PF14833; NAD_binding_11; 1;
PF03446; NAD_binding_2; 1;
TIGRFAMs TIGR01505; tartro_sem_red; 1;
PIRSF PIRSF000103; HIBADH; 1;

Features [?]

From: GARR_ECOLI (P0ABQ2)
Key     From     To       Description   Tag   Condition   FTGroup
NP_BIND     4     18       NAD        
ACT_SITE     170     170             K  
BINDING     95     95       NAD     S  
BINDING     238     238       NAD     K  

Additional information [?]

Size range 276-302 amino acids
Related rules None
Fusion None